Tecrl Gene Detail

Summary

• Symbol
  Tecrl
• Name
  trans-2,3-enoyl-CoA reductase-like
• Synonyms
  D330017N19Rik, Srd5a2l2

• Feature Type
  protein coding gene
• IDs
  MGI:2444966
  NCBI Gene: 243078

Location & Maps

• Sequence Map
  Chr5:83278145-83355195 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    77051 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 43.00 cM
• Mapping Data
  1 experiment

Homology

• Human Ortholog
  TECRL, trans-2,3-enoyl-CoA reductase like

• Vertebrate Orthologs
  8

• Human Ortholog
  TECRL, trans-2,3-enoyl-CoA reductase like
  Orthology source: HomoloGene, HGNC
• Synonyms
  CPVT3, GPSN2L, SRD5A2L2, TERL
• Links
  HGNC:27365

  NCBI Gene ID: 253017

  neXtProt AC: NX_Q5HYJ1

  UniProt: Q5HYJ1

  
  
• Chr Location
  4q13.1; chr4:64276298-64409509 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 27549
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 macaque, rhesus
  
• HCOP
  human homology predictions: TECRL
• Protein SuperFamily
  synaptic glycoprotein SC2
• Gene Tree
  Tecrl
  

Human Diseases

• Diseases
  1 with human TECRL associations

				Human Disease	Mouse Models
				catecholaminergic polymorphic ventricular tachycardia 3 IDs catecholaminergic polymorphic ventricular tachycardia 3       DOID:0060677 ICD10CM:I47.2 OMIM:614021

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  2
• Radiation induced
  1
• Spontaneous
  1
• Targeted
  2
• Genomic Mutations
  4 involving Tecrl
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  14 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  10
• GO References
  4

• External Resources
  FuncBase

Expression

• cDNA Data
  8

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  GEISHA TECRL

Interactions

• Tecrl interacts with 179 markers (Mir9-1, Mir9-2, Mir9-3, ...) View All

Sequences &
Gene Models

• All Sequences
  27
• RefSeq
  2
• UniProt
  4
• CCDS
  CCDS19375.1
• UniGene
  126783

• VEGA
  OTTMUSG00000024555 (Evidence)
• Ensembl
  ENSMUSG00000049537 (Evidence)
• NCBI Gene
  243078

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000024555	VEGA Gene Model | MGI Sequence Detail	77051	C57BL/6J
transcript	OTTMUST00000060309	VEGA | MGI Sequence Detail	2350	Not Applicable
polypeptide	OTTMUSP00000029412	VEGA | MGI Sequence Detail	361	Not Applicable

Polymorphisms

• SNPs within 2kb
  499 from dbSNP Build 142

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000015609 steroid 5-alpha-reductase 2-like 2 protein
  (term hierarchy)
• EC
  1.3.1.-
• InterPro Domains
  IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal

Molecular
Reagents

• All nucleic 8

  cDNA 8

  
  

  Microarray probesets 3

References

• Summaries
  All 30

  Gene Ontology 4

  Phenotypes 8
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42