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Tecrl Gene Detail
Summary
  • Symbol
    Tecrl
  • Name
    trans-2,3-enoyl-CoA reductase-like
  • Synonyms
    D330017N19Rik, Srd5a2l2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444966
    NCBI Gene: 243078
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:83278145-83355195 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.00 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    499 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444966
 protein coding gene Chr5:83278122-83355195 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029661
 protein coding gene Chr5:83956708-84027121 (-)
A/J MGP_AJ_G0029629
 protein coding gene Chr5:80537326-80617064 (-)
AKR/J MGP_AKRJ_G0029577
 protein coding gene Chr5:83233331-83313410 (-)
BALB/cJ MGP_BALBcJ_G0029638
 protein coding gene Chr5:81399896-81485524 (-)
C3H/HeJ MGP_C3HHeJ_G0029361
 protein coding gene Chr5:83694229-83773104 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030092
 protein coding gene Chr5:87339019-87423191 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027334
 protein coding gene Chr5:76568449-76644687 (-)
CAST/EiJ MGP_CASTEiJ_G0028769
 protein coding gene Chr5:82939112-83022014 (-)
CBA/J MGP_CBAJ_G0029330
 protein coding gene Chr5:90156984-90258405 (-)
DBA/2J MGP_DBA2J_G0029475
 protein coding gene Chr5:80664602-80743841 (-)
FVB/NJ MGP_FVBNJ_G0029436
 protein coding gene Chr5:79734172-79814542 (-)
LP/J MGP_LPJ_G0029562
 protein coding gene Chr5:84355922-84446200 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029464
 protein coding gene Chr5:94378170-94479519 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030125
 protein coding gene Chr5:82793475-82884480 (-)
PWK/PhJ MGP_PWKPhJ_G0028493
 protein coding gene Chr5:79698990-79780915 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028327
 protein coding gene Chr5:82149051-82230992 (-)
WSB/EiJ MGP_WSBEiJ_G0028850
 protein coding gene Chr5:83149126-83232237 (-)



Homology
more
  • Human Ortholog
    TECRL, trans-2,3-enoyl-CoA reductase like
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TECRL, trans-2,3-enoyl-CoA reductase like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CPVT3, GPSN2L, SRD5A2L2, TERL
  • Links
    NCBI Gene ID: 253017
    neXtProt AC: NX_Q5HYJ1
    UniProt: Q5HYJ1

  • Chr Location
    4q13.1; chr4:64276298-64409509 (-)  GRCh38.p7
Human Diseases
more
  • Diseases
    1 with human TECRL associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    9
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049537 Ensembl Gene Model | MGI Sequence Detail 77051 C57BL/6J ±  kb
transcript ENSMUST00000053543 Ensembl | MGI Sequence Detail 2350 Not Applicable  
polypeptide ENSMUSP00000062122 Ensembl | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000015609 steroid 5-alpha-reductase 2-like 2 protein
    (term hierarchy)
  • EC
    1.3.1.-
  • InterPro Domains
    IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
    IPR039357 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Gene Ontology 4
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/14/2020
MGI 6.14 		The Jackson Laboratory