About   Help   FAQ
Taf6l Gene Detail
Summary
  • Symbol
    Taf6l
  • Name
    TATA-box binding protein associated factor 6 like
  • Synonyms
    2810417N14Rik, C530024J06Rik, PAF65A
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444957
    NCBI Gene: 225895
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:8751851-8763781 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 5.56 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    34 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444957
 protein coding gene Chr19:8751718-8763781 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024808
 protein coding gene Chr19:6048945-6066943 (-)
A/J MGP_AJ_G0024776
 protein coding gene Chr19:5724520-5738907 (-)
AKR/J MGP_AKRJ_G0024751
 protein coding gene Chr19:5812684-5828213 (-)
BALB/cJ MGP_BALBcJ_G0024776
 protein coding gene Chr19:5829254-5843596 (-)
C3H/HeJ MGP_C3HHeJ_G0024542
 protein coding gene Chr19:5893679-5907380 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025223
 protein coding gene Chr19:6170200-6185766 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022652
 protein coding gene Chr19:5969133-5984343 (-)
CAST/EiJ MGP_CASTEiJ_G0024015
 protein coding gene Chr19:5545018-5560086 (-)
CBA/J MGP_CBAJ_G0024516
 protein coding gene Chr19:6288685-6302352 (-)
DBA/2J MGP_DBA2J_G0024643
 protein coding gene Chr19:5556065-5569947 (-)
FVB/NJ MGP_FVBNJ_G0024610
 protein coding gene Chr19:5630195-5643844 (-)
LP/J MGP_LPJ_G0024730
 protein coding gene Chr19:5937519-5951697 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024637
 protein coding gene Chr19:6153264-6170893 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025272
 protein coding gene Chr19:5857645-5872269 (-)
PWK/PhJ MGP_PWKPhJ_G0023760
 protein coding gene Chr19:5224492-5238443 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023565
 protein coding gene Chr19:5458605-5475575 (-)
WSB/EiJ MGP_WSBEiJ_G0024077
 protein coding gene Chr19:5825358-5841504 (-)



Homology
more
  • Human Ortholog
    TAF6L, TATA-box binding protein associated factor 6 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TAF6L, TATA-box binding protein associated factor 6 like
  • Synonyms
    PAF65A
  • Links
    NCBI Gene ID: 10629
    neXtProt AC: NX_Q9Y6J9
    UniProt: Q9Y6J9

  • Chr Location
    11q12.3; chr11:62771357-62787342 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003680 Ensembl Gene Model | MGI Sequence Detail 11931 C57BL/6J ±  kb
transcript ENSMUST00000177216 Ensembl | MGI Sequence Detail 2167 Not Applicable  
polypeptide ENSMUSP00000135220 Ensembl | MGI Sequence Detail 623 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000016032 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
    (term hierarchy)
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR009072 Histone-fold
    IPR011442 TAF6, C-terminal HEAT repeat domain
    IPR046344 TAF6, C-terminal HEAT repeat domain superfamily
    IPR004823 TATA box binding protein associated factor (TAF), histone-like fold domain
    IPR037796 Transcription initiation factor TFIID subunit 6
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922868, MGI:3035057
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 6
  • Earliest
    J:320277 Ogryzko VV, et al., Histone-like TAFs within the PCAF histone acetylase complex. Cell. 1998 Jul 10;94(1):35-44
  • Latest
    J:278440 Seruggia D, et al., TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network. Mol Cell. 2019 Jun 20;74(6):1148-1163.e7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory