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Mical2 Gene Detail
Summary
  • Symbol
    Mical2
  • Name
    microtubule associated monooxygenase, calponin and LIM domain containing 2
  • Synonyms
    5330438E18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444947
    NCBI Gene: 320878
  • Gene Overview
    MyGene.info: MICAL2
Location & Maps
more
  • Sequence Map
    Chr7:112225856-112355194 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      129339 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 58.74 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MICAL2, microtubule associated monooxygenase, calponin and LIM domain containing 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MICAL2, microtubule associated monooxygenase, calponin and LIM domain containing 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MICAL-2, MICAL2PV1, MICAL2PV2
  • Links
    NCBI Gene ID: 9645
    neXtProt AC: NX_O94851

  • Chr Location
    11p15.3; chr11:12110576-12281016 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    3
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Mical2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023847 VEGA Gene Model | MGI Sequence Detail 129339 C57BL/6J ±  kb
transcript OTTMUST00000058251 VEGA | MGI Sequence Detail 3352 Not Applicable  
polypeptide OTTMUSP00000028195 VEGA | MGI Sequence Detail 1102 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1723 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:201326 Lee BC, et al., MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Mol Cell. 2013 Aug 8;51(3):397-404

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory