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Tmco3 Gene Detail
Summary
  • Symbol
    Tmco3
  • Name
    transmembrane and coiled-coil domains 3
  • Synonyms
    B230339H12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444946
    NCBI Gene: 234076
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:13288190-13322924 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 5.73 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    433 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444946
protein coding gene Chr8:13287913-13322924 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033377
protein coding gene Chr8:10627615-10666126 (+)
A/J MGP_AJ_G0033357
protein coding gene Chr8:10241087-10280925 (+)
AKR/J MGP_AKRJ_G0033288
protein coding gene Chr8:10523225-10559929 (+)
BALB/cJ MGP_BALBcJ_G0033358
protein coding gene Chr8:10374909-10411449 (+)
C3H/HeJ MGP_C3HHeJ_G0033071
protein coding gene Chr8:10730793-10772737 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033870
protein coding gene Chr8:11000999-11035460 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030839
protein coding gene Chr8:9746343-9781303 (+)
CAST/EiJ MGP_CASTEiJ_G0032393
protein coding gene Chr8:10490999-10533056 (+)
CBA/J MGP_CBAJ_G0033044
protein coding gene Chr8:11458645-11502883 (+)
DBA/2J MGP_DBA2J_G0033197
protein coding gene Chr8:10190369-10227356 (+)
FVB/NJ MGP_FVBNJ_G0033146
protein coding gene Chr8:10207354-10242666 (+)
LP/J MGP_LPJ_G0033291
protein coding gene Chr8:10534118-10574706 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033180
protein coding gene Chr8:11689963-11727196 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033887
protein coding gene Chr8:10580171-10621222 (+)
PWK/PhJ MGP_PWKPhJ_G0032106
protein coding gene Chr8:10243002-10280029 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031948
protein coding gene Chr8:10472296-10508804 (+)
WSB/EiJ MGP_WSBEiJ_G0032509
protein coding gene Chr8:10616834-10654604 (+)



Homology
more
  • Human Ortholog
    TMCO3, transmembrane and coiled-coil domains 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMCO3, transmembrane and coiled-coil domains 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C13orf11
  • Links
    NCBI Gene ID: 55002
    neXtProt AC: NX_Q6UWJ1
    UniProt: Q6UWJ1

  • Chr Location
    13q34; chr13:113490993-113550229 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 32376
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TMCO3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038497 Ensembl Gene Model | MGI Sequence Detail 34735 C57BL/6J ±  kb
transcript ENSMUST00000045229 Ensembl | MGI Sequence Detail 4335 Not Applicable  
polypeptide ENSMUSP00000040347 Ensembl | MGI Sequence Detail 678 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142882
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory