About   Help   FAQ
Ckap4 Gene Detail
Summary
  • Symbol
    Ckap4
  • Name
    cytoskeleton-associated protein 4
  • Synonyms
    5630400A09Rik, CLIMP-63, P63
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444926
    NCBI Gene: 216197
  • Gene Overview
    MyGene.info: CKAP4
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:84526305-84533888 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 41.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    62 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444926
protein coding gene Chr10:84526305-84534062 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017591
protein coding gene Chr10:85399123-85406854 (-)
A/J MGP_AJ_G0017571
protein coding gene Chr10:82499238-82506969 (-)
AKR/J MGP_AKRJ_G0017530
protein coding gene Chr10:84790097-84797828 (-)
BALB/cJ MGP_BALBcJ_G0017534
protein coding gene Chr10:82748688-82756419 (-)
C3H/HeJ MGP_C3HHeJ_G0017356
protein coding gene Chr10:84874319-84882050 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017991
protein coding gene Chr10:88290646-88298377 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015675
protein coding gene Chr10:78323303-78330963 (-)
CAST/EiJ MGP_CASTEiJ_G0016923
protein coding gene Chr10:84726231-84733977 (-)
CBA/J MGP_CBAJ_G0017326
protein coding gene Chr10:91996505-92004236 (-)
DBA/2J MGP_DBA2J_G0017432
protein coding gene Chr10:81642310-81650041 (-)
FVB/NJ MGP_FVBNJ_G0017426
protein coding gene Chr10:80874766-80882497 (-)
LP/J MGP_LPJ_G0017504
protein coding gene Chr10:86036305-86044036 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017454
protein coding gene Chr10:93595236-93602967 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018028
protein coding gene Chr10:84712373-84720107 (-)
PWK/PhJ MGP_PWKPhJ_G0016704
protein coding gene Chr10:81501493-81509239 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016493
protein coding gene Chr10:83336615-83345947 (-)
WSB/EiJ MGP_WSBEiJ_G0016982
protein coding gene Chr10:84704626-84712348 (-)



Homology
more
  • Human Ortholog
    CKAP4, cytoskeleton associated protein 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CKAP4, cytoskeleton associated protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLIMP-63, ERGIC-63, p63
  • Links
    NCBI Gene ID: 10970
    neXtProt AC: NX_Q07065
    UniProt: Q07065

  • Chr Location
    12q23.3; chr12:106237881-106247935 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4970
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CKAP4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 216197 NCBI Gene Model | MGI Sequence Detail 7584 C57BL/6J ±  kb
    transcript NM_175451 RefSeq | MGI Sequence Detail 2915 C57BL/6  
    polypeptide Q8BMK4 UniProt | EBI | MGI Sequence Detail 575 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 127
      cDNA 127

      Microarray probesets 10
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 12
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:247120 Osseni A, et al., Triadin and CLIMP-63 form a link between triads and microtubules in muscle cells. J Cell Sci. 2016 Oct 15;129(20):3744-3755

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory