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Zfp438 Gene Detail
Summary
  • Symbol
    Zfp438
  • Name
    zinc finger protein 438
  • Synonyms
    9430091M14Rik, B830013J05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444919
    NCBI Gene: 240186
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:5210029-5334807 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 3.02 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2695 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444919
 protein coding gene Chr18:5210027-5334826 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024126
 protein coding gene Chr18:2064470-2189473 (-)
A/J MGP_AJ_G0024088
 protein coding gene Chr18:2091572-2215888 (-)
AKR/J MGP_AKRJ_G0024056
 protein coding gene Chr18:2100540-2228938 (-)
BALB/cJ MGP_BALBcJ_G0024088
 protein coding gene Chr18:2077418-2198137 (-)
C3H/HeJ MGP_C3HHeJ_G0023853
 protein coding gene Chr18:2068716-2192129 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024533
 protein coding gene Chr18:2217023-2347684 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021972
 protein coding gene Chr18:1879469-1995764 (-)
CAST/EiJ MGP_CASTEiJ_G0023332
 protein coding gene Chr18:2037067-2172025 (-)
CBA/J MGP_CBAJ_G0023827
 protein coding gene Chr18:2204077-2342164 (-)
DBA/2J MGP_DBA2J_G0023955
 protein coding gene Chr18:2025218-2139530 (-)
FVB/NJ MGP_FVBNJ_G0023921
 protein coding gene Chr18:1992168-2119037 (-)
LP/J MGP_LPJ_G0024039
 protein coding gene Chr18:2166772-2291898 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023949
 protein coding gene Chr18:2227257-2359603 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024578
 protein coding gene Chr18:2038193-2165670 (-)
PWK/PhJ MGP_PWKPhJ_G0023077
 protein coding gene Chr18:2004233-2131570 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022888
 protein coding gene Chr18:2313850-2436567 (-)
WSB/EiJ MGP_WSBEiJ_G0023398
 protein coding gene Chr18:2063706-2188721 (-)



Homology
more
  • Human Ortholog
    ZNF438, zinc finger protein 438
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF438, zinc finger protein 438
  • Synonyms
    bA330O11.1
  • Links
    NCBI Gene ID: 220929
    UniProt: Q7Z4V0

  • Chr Location
    10p11.23; chr10:30820207-31032411 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    24
  • cDNA Data
    19
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050945 Ensembl Gene Model | MGI Sequence Detail 124779 C57BL/6J ±  kb
transcript ENSMUST00000063989 Ensembl | MGI Sequence Detail 3211 Not Applicable  
polypeptide ENSMUSP00000067049 Ensembl | MGI Sequence Detail 798 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 20
    cDNA 19
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1924617
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory