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Enox1 Gene Detail
Summary
  • Symbol
    Enox1
  • Name
    ecto-NOX disulfide-thiol exchanger 1
  • Synonyms
    D230005D02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444896
    NCBI Gene: 239188
Location & Maps
more
  • Sequence Map
    Chr14:77156763-77721760 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      564998 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 40.63 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ENOX1, ecto-NOX disulfide-thiol exchanger 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ENOX1, ecto-NOX disulfide-thiol exchanger 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    bA64J21.1, cCNOX, CNOX, PIG38
  • Links
    NCBI Gene ID: 55068
    neXtProt AC: NX_Q8TC92

  • Chr Location
    13q14.11; chr13:43213130-43786980 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 56793
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ENOX1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    142
  • Chemically induced (other)
    1
  • Gene trapped
    138
  • Targeted
    3
  • Genomic Mutations
    1 involving Enox1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022012 Ensembl Gene Model | MGI Sequence Detail 564998 C57BL/6J ±  kb
transcript ENSMUST00000022589 Ensembl | MGI Sequence Detail 3495 Not Applicable  
polypeptide ENSMUSP00000022589 Ensembl | MGI Sequence Detail 643 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    5431 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000007085 ecto-NOX disulfide-thiol exchanger 1
  • EC
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory