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Dglucy Gene Detail
Summary
  • Symbol
    Dglucy
  • Name
    D-glutamate cyclase
  • Synonyms
    9030617O03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444813
    NCBI Gene: 217830
  • Gene Overview
    MyGene.info: DGLUCY
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:100779071-100872610 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 51.10 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    764 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444813
protein coding gene Chr12:100779057-100896981 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020020
protein coding gene Chr12:102263801-102384095 (+)
A/J MGP_AJ_G0019975
protein coding gene Chr12:98423433-98530067 (+)
AKR/J MGP_AKRJ_G0019951
protein coding gene Chr12:101097703-101223048 (+)
BALB/cJ MGP_BALBcJ_G0019961
protein coding gene Chr12:98770285-98882854 (+)
C3H/HeJ MGP_C3HHeJ_G0019763
protein coding gene Chr12:101630294-101752305 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020410
protein coding gene Chr12:105439809-105557385 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018024
protein coding gene Chr12:95394332-95510521 (+)
CAST/EiJ MGP_CASTEiJ_G0019309
protein coding gene Chr12:96744500-96863616 (+)
CBA/J MGP_CBAJ_G0019735
protein coding gene Chr12:109319725-109459055 (+)
DBA/2J MGP_DBA2J_G0019846
protein coding gene Chr12:97863760-97982420 (+)
FVB/NJ MGP_FVBNJ_G0019835
protein coding gene Chr12:96585758-96701914 (+)
LP/J MGP_LPJ_G0019922
protein coding gene Chr12:102119081-102240140 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019877
protein coding gene Chr12:112913122-113041669 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020439
protein coding gene Chr12:100667727-100792390 (+)
PWK/PhJ MGP_PWKPhJ_G0019073
protein coding gene Chr12:92506979-92622558 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018869
protein coding gene Chr12:94860616-94978222 (+)
WSB/EiJ MGP_WSBEiJ_G0019363
protein coding gene Chr12:101529048-101656649 (+)



Homology
more
  • Human Ortholog
    DGLUCY, D-glutamate cyclase
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DGLUCY, D-glutamate cyclase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf159
  • Links
    NCBI Gene ID: 80017
    neXtProt AC: NX_Q7Z3D6
    UniProt: Q7Z3D6

  • Chr Location
    14q32.11; chr14:91114013-91225396 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit elevated D-glutamate levels in the heart.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 217830 NCBI Gene Model | MGI Sequence Detail 93540 C57BL/6J ±  kb
transcript NM_001361017 RefSeq | MGI Sequence Detail 3461 C57BL/6  
polypeptide Q8BH86 UniProt | EBI | MGI Sequence Detail 617 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:241368 Ariyoshi M, et al., D-Glutamate is metabolized in the heart mitochondria. Sci Rep. 2017 Mar 07;7:43911

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory