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Atad2b Gene Detail
Summary
  • Symbol
    Atad2b
  • Name
    ATPase family, AAA domain containing 2B
  • Synonyms
    1110014E10Rik, D530031C13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444798
    NCBI Gene: 320817
Location & Maps
more
  • Sequence Map
    Chr12:4917404-5044047 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      126644 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 2.15 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ATAD2B, ATPase family, AAA domain containing 2B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ATAD2B, ATPase family, AAA domain containing 2B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 54454
    neXtProt AC: NX_Q9ULI0

  • Chr Location
    2p24.1-p23.3; chr2:23685229-23927114 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption exhibit reduced body size and fertility in female mice.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052812 Ensembl Gene Model | MGI Sequence Detail 126644 C57BL/6J ±  kb
transcript ENSMUST00000045664 Ensembl | MGI Sequence Detail 4688 Not Applicable  
polypeptide ENSMUSP00000047445 Ensembl | MGI Sequence Detail 1460 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    522 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    Genomic 1
    cDNA 75

    Microarray probesets 4
Other
Accession IDs
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MGI:1915840, MGI:2145096, MGI:3040673
References
more
  • Summaries
    All 32
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory