Dcaf5 Gene Detail

Summary

• Symbol
  Dcaf5
• Name
  DDB1 and CUL4 associated factor 5
• Synonyms
  9430020B07Rik, BCRG2, BCRP2, mKIAA1824, Wdr22

• Feature Type
  protein coding gene
• IDs
  MGI:2444785
  NCBI Gene: 320808
• Alliance
  gene page

Location & Maps

• Sequence Map
  Chr12:80335848-80436601 bp, - strand
• From Ensembl annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    100754 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, 36.61 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  DCAF5, DDB1 and CUL4 associated factor 5

• Vertebrate Orthologs
  10

• Human Ortholog
  DCAF5, DDB1 and CUL4 associated factor 5
  Orthology source: HomoloGene, HGNC
• Synonyms
  BCRG2, BCRP2, D14S1461E, WDR22
• Links
  HGNC:20224

  NCBI Gene ID: 8816

  neXtProt AC: NX_Q96JK2

  UniProt: Q96JK2

  
  
• Chr Location
  14q24.1; chr14:69050920-69153393 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 18564
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: DCAF5
• Gene Tree
  Dcaf5
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Gene trapped
  1
• Targeted
  3
• Genomic Mutations
  1 involving Dcaf5
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  17 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

• External Resources
  FuncBase

Expression

• cDNA Data
  11

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase dcaf5

Interactions

• Dcaf5 interacts with 333 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  32
• RefSeq
  4
• UniProt
  2
• CCDS
  CCDS26013.1

• Ensembl
  ENSMUSG00000049106 (Evidence)
• NCBI Gene
  320808

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000049106	Ensembl Gene Model | MGI Sequence Detail	100754	C57BL/6J
transcript	ENSMUST00000054145	Ensembl | MGI Sequence Detail	5706	Not Applicable
polypeptide	ENSMUSP00000052755	Ensembl | MGI Sequence Detail	946	Not Applicable

Polymorphisms

• SNPs within 2kb
  419 from dbSNP Build 142

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000031463 DDB1- and CUL4-associated factor 5
  (term hierarchy)
• InterPro Domains
  IPR001680 WD40 repeat
  IPR017986 WD40-repeat-containing domain
  IPR036322 WD40-repeat-containing domain superfamily
  IPR015943 WD40/YVTN repeat-like-containing domain superfamily

Molecular
Reagents

• All nucleic 11

  cDNA 11

  
  

  Microarray probesets 6

Other
Accession IDs

MGI:2144792, MGI:2144823, MGI:2144898, MGI:2145009

References

• Summaries
  All 29

  Gene Ontology 2

  Phenotypes 5
• Earliest
  J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582