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Dcaf5 Gene Detail
Summary
  • Symbol
    Dcaf5
  • Name
    DDB1 and CUL4 associated factor 5
  • Synonyms
    9430020B07Rik, BCRG2, BCRP2, mKIAA1824, Wdr22
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444785
    NCBI Gene: 320808
Location & Maps
more
  • Sequence Map
    Chr12:80335847-80436601 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      100755 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 36.61 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DCAF5, DDB1 and CUL4 associated factor 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DCAF5, DDB1 and CUL4 associated factor 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BCRG2, BCRP2, D14S1461E, WDR22
  • Links
    NCBI Gene ID: 8816
    neXtProt AC: NX_Q96JK2

  • Chr Location
    14q24.1; chr14:69050920-69153393 (-)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 18564
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: DCAF5
  • Gene Tree
    Dcaf5
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Dcaf5
  • Incidental Mutations
    Mutagenetix , APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    11
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320808 NCBI Gene Model | MGI Sequence Detail 100755 C57BL/6J ±  kb
transcript NM_177267 RefSeq | MGI Sequence Detail 5707 C57BL/6  
polypeptide Q80T85 UniProt | EBI | MGI Sequence Detail 946 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    419 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031463 DDB1- and CUL4-associated factor 5
  • InterPro Domains
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 6
Other
Accession IDs
less
MGI:2144792, MGI:2144823, MGI:2144898, MGI:2145009
References
more
  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory