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Gfm2 Gene Detail
Summary
  • Symbol
    Gfm2
  • Name
    G elongation factor, mitochondrial 2
  • Synonyms
    6530419G12Rik, A930009M04Rik, EFG2, MST027
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444783
    NCBI Gene: 320806
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:97137937-97181195 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 50.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    282 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444783
protein coding gene Chr13:97137937-97181196 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020858
protein coding gene Chr13:98734546-98781492 (+)
A/J MGP_AJ_G0020812
protein coding gene Chr13:95000511-95043501 (+)
AKR/J MGP_AKRJ_G0020786
protein coding gene Chr13:97893283-97944756 (+)
BALB/cJ MGP_BALBcJ_G0020809
protein coding gene Chr13:95684232-95728205 (+)
C3H/HeJ MGP_C3HHeJ_G0020601
protein coding gene Chr13:97618954-97665365 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021244
protein coding gene Chr13:101712616-101759765 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018814
protein coding gene Chr13:90762804-90807709 (+)
CAST/EiJ MGP_CASTEiJ_G0020120
protein coding gene Chr13:96928636-96974911 (+)
CBA/J MGP_CBAJ_G0020561
protein coding gene Chr13:105773668-105822434 (+)
DBA/2J MGP_DBA2J_G0020686
protein coding gene Chr13:94753070-94796465 (+)
FVB/NJ MGP_FVBNJ_G0020667
protein coding gene Chr13:93520443-93564328 (+)
LP/J MGP_LPJ_G0020761
protein coding gene Chr13:98844320-98890507 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020695
protein coding gene Chr13:106116770-106164497 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021285
protein coding gene Chr13:97317929-97362400 (+)
PWK/PhJ MGP_PWKPhJ_G0019872
protein coding gene Chr13:93533107-93578313 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019696
protein coding gene Chr13:93599793-93643716 (+)
WSB/EiJ MGP_WSBEiJ_G0020177
protein coding gene Chr13:97771929-97819085 (+)



Homology
more
  • Human Ortholog
    GFM2, G elongation factor mitochondrial 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GFM2, G elongation factor mitochondrial 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EFG2, EF-G2mt, hEFG2, mEF-G 2, MRRF2, MST027, MSTP027, RRF, RRF2, RRF2mt
  • Links
    NCBI Gene ID: 84340
    neXtProt AC: NX_Q969S9
    UniProt: Q969S9

  • Chr Location
    5q13.3; chr5:74721204-74767371 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021666 Ensembl Gene Model | MGI Sequence Detail 43259 C57BL/6J ±  kb
transcript ENSMUST00000161639 Ensembl | MGI Sequence Detail 3157 Not Applicable  
polypeptide ENSMUSP00000125656 Ensembl | MGI Sequence Detail 779 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000007944 elongation factor G 2, mitochondrial
  • InterPro Domains
    IPR035647 EF-G domain III/V-like
    IPR035649 EFG, domain V
    IPR000640 Elongation factor EFG, domain V-like
    IPR041095 Elongation Factor G, domain II
    IPR009022 Elongation factor G, domain III
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR020568 Ribosomal protein S5 domain 2-type fold
    IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
    IPR030851 Ribosome-releasing factor 2, mitochondrial
    IPR005225 Small GTP-binding protein domain
    IPR000795 Transcription factor, GTP-binding domain
    IPR005517 Translation elongation factor EFG/EF2, domain IV
    IPR009000 Translation protein, beta-barrel domain superfamily
    IPR031157 Tr-type G domain, conserved site
Molecular
Reagents
less
  • All nucleic 71
    cDNA 71

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925484
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory