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Zfp418 Gene Detail
Summary
  • Symbol
    Zfp418
  • Name
    zinc finger protein 418
  • Synonyms
    A230102I05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444763
    NCBI Gene: 232854
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:7171353-7183560 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 4.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444763
protein coding gene Chr7:7171330-7183562 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031618
protein coding gene Chr7:4274749-4286981 (+)
A/J MGP_AJ_G0031593
protein coding gene Chr7:4142957-4155177 (+)
AKR/J MGP_AKRJ_G0031519
protein coding gene Chr7:4435386-4447642 (+)
BALB/cJ MGP_BALBcJ_G0031601
protein coding gene Chr7:4249805-4262037 (+)
C3H/HeJ MGP_C3HHeJ_G0031321
protein coding gene Chr7:4273226-4285458 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032063
protein coding gene Chr7:4508315-4520545 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029175
protein coding gene Chr7:3786659-3799127 (+)
CAST/EiJ MGP_CASTEiJ_G0030683
protein coding gene Chr7:4160143-4172354 (+)
CBA/J MGP_CBAJ_G0031278
protein coding gene Chr7:4672742-4685092 (+)
DBA/2J MGP_DBA2J_G0031436
protein coding gene Chr7:4229906-4242138 (+)
FVB/NJ MGP_FVBNJ_G0031390
protein coding gene Chr7:4161181-4173421 (+)
LP/J MGP_LPJ_G0031522
protein coding gene Chr7:4398262-4410476 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031429
protein coding gene Chr7:4667633-4680778 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032092
protein coding gene Chr7:4200970-4213599 (+)
PWK/PhJ MGP_PWKPhJ_G0030410
protein coding gene Chr7:4353003-4365221 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030237
protein coding gene Chr7:3720777-3735283 (+)
WSB/EiJ MGP_WSBEiJ_G0030777
protein coding gene Chr7:4351256-4363452 (+)



Homology
more
  • Human Ortholog
    ZNF416, zinc finger protein 416
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZNF416, zinc finger protein 416
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 55659
    neXtProt AC: NX_Q9BWM5
    UniProt: Q9BWM5

  • Chr Location
    19q13.43; chr19:57571015-57578938 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 232854 NCBI Gene Model | MGI Sequence Detail 12208 C57BL/6J ±  kb
    transcript NM_146179 RefSeq | MGI Sequence Detail 2700 C57BL/6  
    polypeptide NP_666291 RefSeq | MGI Sequence Detail 652 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 2
    References
    more
    • Summaries
      All 18
      Developmental Gene Expression 1
      Phenotypes 3
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:251673 Pan L, et al., Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis. PLoS One. 2017;12(10):e0186635

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    11/26/2019
    MGI 6.14
    The Jackson Laboratory