About   Help   FAQ
Shisa2
Gene Detail
Symbol

Name
ID
Shisa2
shisa family member 2
MGI:2444716
Synonyms
9430059P22Rik, MAd2, mShisa, shisa, Tmem46
Feature Type
protein coding gene
Genetic Map
Chromosome 14
31.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:59625281-59631658 bp, + strand
From Ensembl annotation of GRCm38

  6378 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17078  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Shisa2

Human
homologs
Human Homolog SHISA2, shisa family member 2
NCBI Gene ID 387914
neXtProt AC  NX_Q6UWI4
Human Synonyms  bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166
Human Chr (Location)  13q12.13; chr13:26044597-26051060 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
 
Mice homozygous for a null alle exhibit dwarfism, delayed growth and postnatal lethality with abnormal hypothalamus morphology.
 
Interactions
Shisa2 interacts with 197 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process multicellular organismal development
Component endoplasmic reticulum, integral component of membrane, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (103)    Tissues (70)    Images (48)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
In situ reporter (knock in) 6
Northern blot 1
RT-PCR 2
cDNA source data(46)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(46) Primer pair(1) Other(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000044461 (Evidence)
Entrez Gene219134 (Evidence)
UniGene275409
DFCITC1577913
DoTSDT.101315222
NIA Mouse Gene IndexU015709
Consensus CDS ProjectCCDS27173.1
International Mouse Knockout Project StatusShisa2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044461 Ensembl Gene Model | MGI Sequence Detail 6378 C57BL/6J ±  kb
transcript ENSMUST00000053949 Ensembl | MGI Sequence Detail 3144 Not Applicable 
polypeptide ENSMUSP00000059391 Ensembl | MGI Sequence Detail 295 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026910 Shisa family
Protein Ontology PR:000014842 protein shisa-2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:194049 Johansson PA, et al., The transcription factor Otx2 regulates choroid plexus development and function. Development. 2013 Mar;140(5):1055-66
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory