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Dpy19l2
Gene Detail
 Symbol
Name
ID
Dpy19l2
dpy-19-like 2 (C. elegans)
MGI:2444662
Synonyms 4932443J21Rik
Feature Type protein coding gene
Genetic Map
Chromosome 9
10.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:24557048-24696293 bp, - strand
From NCBI annotation of GRCm38

  139246 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77569  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Dpy19l2

Human
homologs
Human Homolog DPY19L2, dpy-19-like 2 (C. elegans)
NCBI Gene ID 283417
neXtProt AC  NX_Q6NUT2
Human Synonyms  SPATA34, SPGF9
Human Chr (Location)  12q14.2; chr12:63558913-63669201 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human DPY19L2
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit male sterility associated with globozoospermia.
 
Gene Ontology
(GO)
classifications
All GO classifications: (50 annotations)
Process cell differentiation, multicellular organismal development, ...
Component integral component of membrane, membrane, ...
Function 1,2-dihydroxy-phenanthrene glycosyltransferase activity, 1-phenanthrol glycosyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(3)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000085576 (Evidence)
Entrez Gene320752 (Evidence)
UniGene46158
DFCITC1597439
DoTSDT.101718839
NIA Mouse Gene IndexU030620
EC2.4.1.-
Consensus CDS ProjectCCDS52743.1
International Mouse Knockout Project StatusDpy19l2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 320752 NCBI Gene Model | MGI Sequence Detail 139246 C57BL/6J ±  kb
transcript NM_001166207 RefSeq | MGI Sequence Detail 3441 C57BL/6 
polypeptide P0CW70 UniProt | EBI | MGI Sequence Detail 773 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(802 from dbSNP Build 137)    SNPs within 2kb including multiple locations(804)
Protein-related
information
ResourceIDDescription
InterPro IPR018732 Dpy-19
Protein Ontology PR:000006672 protein dpy-19 2
Graphical View of Protein Domain Structure
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:187630 Pierre V, et al., Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus. Development. 2012 Aug;139(16):2955-65
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory