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Dpy19l2
Gene Detail
Symbol

Name
ID
Dpy19l2
dpy-19-like 2 (C. elegans)
MGI:2444662
Synonyms
4932443J21Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
10.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:24557048-24696293 bp, - strand
From Ensembl annotation of GRCm38

  139246 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77569  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: DPY19L2
Gene Tree: Dpy19l2

Human
homologs
DPY19L2, dpy-19-like 2 (C. elegans)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 283417
neXtProt AC: NX_Q6NUT2

Human Synonyms: SPATA34, SPGF9

Human Chr (Location): 12q14.2; chr12:63558913-63669201 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DPY19L2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit male sterility associated with globozoospermia.
 
Interactions
Dpy19l2 interacts with 177 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(3)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000085576 (Evidence)
Entrez Gene 320752 (Evidence)
UniGene 46158
DFCI TC1597439
DoTS DT.101718839
NIA Mouse Gene Index U030620
EC 2.4.1.-
Consensus CDS Project CCDS52743.1
International Mouse Phenotyping Consortium Status Dpy19l2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000085576 Ensembl Gene Model | MGI Sequence Detail 139246 C57BL/6J ±  kb
transcript ENSMUST00000133010 Ensembl | MGI Sequence Detail 3441 Not Applicable 
polypeptide ENSMUSP00000132092 Ensembl | MGI Sequence Detail 773 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(13) UniProt(1)
Polymorphisms
SNPs within 2kb(802 from dbSNP Build 137)    SNPs within 2kb including multiple locations(804)
Protein-related
information
ResourceIDDescription
InterPro IPR018732 Dpy-19
Protein Ontology PR:000006672 protein dpy-19 2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:187630 Pierre V, et al., Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus. Development. 2012 Aug;139(16):2955-65
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory