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Lingo4 Gene Detail
Summary
  • Symbol
    Lingo4
  • Name
    leucine rich repeat and Ig domain containing 4
  • Synonyms
    A530050P17Rik, LERN4, Lrrn6d
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444651
    NCBI Gene: 320747
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:94399219-94404501 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444651
protein coding gene Chr3:94398517-94404501 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027548
protein coding gene Chr3:94971995-94977992 (+)
A/J MGP_AJ_G0027507
protein coding gene Chr3:92082021-92088012 (+)
AKR/J MGP_AKRJ_G0027475
protein coding gene Chr3:94172602-94178599 (+)
BALB/cJ MGP_BALBcJ_G0027518
protein coding gene Chr3:91784575-91790545 (+)
C3H/HeJ MGP_C3HHeJ_G0027254
protein coding gene Chr3:94463450-94469440 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027967
protein coding gene Chr3:98562662-98568632 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025309
protein coding gene Chr3:88572273-88578240 (+)
CAST/EiJ MGP_CASTEiJ_G0026702
protein coding gene Chr3:93813998-93819992 (+)
CBA/J MGP_CBAJ_G0027230
protein coding gene Chr3:102053295-102059289 (+)
DBA/2J MGP_DBA2J_G0027369
protein coding gene Chr3:91341784-91347775 (+)
FVB/NJ MGP_FVBNJ_G0027339
protein coding gene Chr3:89446306-89452302 (+)
LP/J MGP_LPJ_G0027477
protein coding gene Chr3:96280435-96286431 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027366
protein coding gene Chr3:108286852-108292823 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028021
protein coding gene Chr3:93854750-93860720 (+)
PWK/PhJ MGP_PWKPhJ_G0026430
protein coding gene Chr3:91233668-91239632 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026251
protein coding gene Chr3:92194210-92200163 (+)
WSB/EiJ MGP_WSBEiJ_G0026785
protein coding gene Chr3:94202709-94208674 (+)



Homology
more
  • Human Ortholog
    LINGO4, leucine rich repeat and Ig domain containing 4
  • Vertebrate Orthologs
    7
  • Human Ortholog
    LINGO4, leucine rich repeat and Ig domain containing 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DAAT9248, LRRN6D, PRO34002
  • Links
    NCBI Gene ID: 339398
    neXtProt AC: NX_Q6UY18
    UniProt: Q6UY18

  • Chr Location
    1q21.3; chr1:151800264-151805442 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320747 NCBI Gene Model | MGI Sequence Detail 5283 C57BL/6J ±  kb
transcript NM_001368653 RefSeq | MGI Sequence Detail 4389 C57BL/6  
polypeptide Q149C3 UniProt | EBI | MGI Sequence Detail 593 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 10
    Primer pair 3

    Microarray probesets 1
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:211830 Um JW, et al., Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell Rep. 2014 Mar 27;6(6):1096-109

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory