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Hpdl Gene Detail
Summary
  • Symbol
    Hpdl
  • Name
    4-hydroxyphenylpyruvate dioxygenase-like
  • Synonyms
    A830048M07Rik, Gloxd1, MGC:31514
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444646
    NCBI Gene: 242642
Location & Maps
more
  • Sequence Map
    Chr4:116819904-116821707 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1804 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 53.35 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HPDL, 4-hydroxyphenylpyruvate dioxygenase like
  • Vertebrate Orthologs
    12
  • Human Ortholog
    HPDL, 4-hydroxyphenylpyruvate dioxygenase like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    4-HPPD-L, GLOXD1
  • Links
    NCBI Gene ID: 84842
    neXtProt AC: NX_Q96IR7

  • Chr Location
    1p34.1; chr1:45326873-45328675 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 13109
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;2 zebrafish;2 frog, western clawed
  • HCOP
    human homology predictions: HPDL
  • Protein SuperFamily
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Hpdl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009753 VEGA Gene Model | MGI Sequence Detail 1804 C57BL/6J ±  kb
transcript OTTMUST00000022550 VEGA | MGI Sequence Detail 1804 Not Applicable  
polypeptide OTTMUSP00000010282 VEGA | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    31 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008731 4-hydroxyphenylpyruvate dioxygenase-like protein
  • EC
  • InterPro Domains
    IPR005956 4-hydroxyphenylpyruvate dioxygenase
    IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Molecular
Reagents
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  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
less
MGI:2384306
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory