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Adam6b Gene Detail
Summary
  • Symbol
    Adam6b
  • Name
    a disintegrin and metallopeptidase domain 6B
  • Synonyms
    4930523C11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444636
    NCBI Gene: 238405
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr12:113489565-113491835 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.10 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444636
protein coding gene Chr12:113489511-113492057 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020176
protein coding gene Chr12:116045582-116048235 (+)
A/J MGP_AJ_G0020133
protein coding gene Chr12:111549132-111551784 (+)
AKR/J MGP_AKRJ_G0020108
protein coding gene Chr12:114840939-114843485 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0019920
protein coding gene Chr12:115307300-115377670 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020563
protein coding gene Chr12:119645347-119647893 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0019460
protein coding gene Chr12:110256340-110259775 (+)
CBA/J MGP_CBAJ_G0019887
protein coding gene Chr12:124230744-124233705 (+)
DBA/2J MGP_DBA2J_G0020003
protein coding gene Chr12:111042415-111045065 (+)
FVB/NJ MGP_FVBNJ_G0019988
protein coding gene Chr12:109872886-109875537 (+)
LP/J MGP_LPJ_G0020078
protein coding gene Chr12:115895505-115898051 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020592
protein coding gene Chr12:114291728-114294383 (+)
PWK/PhJ MGP_PWKPhJ_G0019221
protein coding gene Chr12:105769702-105776396 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019026
protein coding gene Chr12:108476797-108479001 (+)
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 238405 NCBI Gene Model | MGI Sequence Detail 2271 C57BL/6J ±  kb
transcript NM_001009545 RefSeq | MGI Sequence Detail 2271 Not Specified  
polypeptide NP_001009545 RefSeq | MGI Sequence Detail 756 Not Specified  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 1
    cDNA 5

    Microarray probesets 4
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:284593 Skokos D, et al., A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies. Sci Transl Med. 2020 Jan 8;12(525)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory