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Kctd3 Gene Detail
Summary
  • Symbol
    Kctd3
  • Name
    potassium channel tetramerisation domain containing 3
  • Synonyms
    4930438A20Rik, E330032J19Rik, NY-REN-45
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444629
    NCBI Gene: 226823
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:188971095-189007841 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 93.51 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444629
protein coding gene Chr1:188971095-189007868 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016926
protein coding gene Chr1:195845780-195883728 (-)
A/J MGP_AJ_G0016905
protein coding gene Chr1:187844729-187882134 (-)
AKR/J MGP_AKRJ_G0016870
protein coding gene Chr1:193357662-193394184 (-)
BALB/cJ MGP_BALBcJ_G0016863
protein coding gene Chr1:188515935-188554035 (-)
C3H/HeJ MGP_C3HHeJ_G0016687
protein coding gene Chr1:194232538-194272269 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017326
protein coding gene Chr1:202125844-202166179 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015033
protein coding gene Chr1:178785554-178822767 (-)
CAST/EiJ MGP_CASTEiJ_G0016270
protein coding gene Chr1:193801451-193841043 (-)
CBA/J MGP_CBAJ_G0016661
protein coding gene Chr1:209638676-209674944 (-)
DBA/2J MGP_DBA2J_G0016767
protein coding gene Chr1:186589439-186626030 (-)
FVB/NJ MGP_FVBNJ_G0016763
protein coding gene Chr1:184691235-184728136 (-)
LP/J MGP_LPJ_G0016842
protein coding gene Chr1:197027424-197068000 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016795
protein coding gene Chr1:216377375-216424501 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017363
protein coding gene Chr1:193290068-193328882 (-)
PWK/PhJ MGP_PWKPhJ_G0016057
protein coding gene Chr1:185839859-185877353 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015833
protein coding gene Chr1:192268279-192303900 (-)
WSB/EiJ MGP_WSBEiJ_G0016332
protein coding gene Chr1:193481479-193517928 (-)



Homology
more
  • Human Ortholog
    KCTD3, potassium channel tetramerization domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCTD3, potassium channel tetramerization domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NY-REN-45
  • Links
    NCBI Gene ID: 51133
    neXtProt AC: NX_Q9Y597
    UniProt: Q9Y597

  • Chr Location
    1q41; chr1:215567185-215621821 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9395
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KCTD3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026608 Ensembl Gene Model | MGI Sequence Detail 36747 C57BL/6J ±  kb
transcript ENSMUST00000085678 Ensembl | MGI Sequence Detail 3706 Not Applicable  
polypeptide ENSMUSP00000082821 Ensembl | MGI Sequence Detail 815 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 6
Other
Accession IDs
less
MGI:1921220
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:203510 Cao-Ehlker X, et al., Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3). J Biol Chem. 2013 Mar 15;288(11):7580-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory