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Mysm1
Gene Detail
Symbol

Name
ID
Mysm1
myb-like, SWIRM and MPN domains 1
MGI:2444584
Synonyms
C130067A03Rik, C530050H10Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
43.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:94942040-94979100 bp, - strand
From VEGA annotation of GRCm38

  37061 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:66204  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mysm1

Human
homologs
Human Homolog MYSM1, myb-like, SWIRM and MPN domains 1
NCBI Gene ID 114803
neXtProt AC  NX_Q5VVJ2
Human Synonyms  2ADUB, 2A-DUB
Human Chr (Location)  1p32.1; chr1:58654739-58700075 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from APF )
Interactions
Mysm1 interacts with 423 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process chromatin modification, chromatin remodeling, ...
Component nucleus
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (2)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 2
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(11) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000007999 (Evidence)
Ensembl Gene ModelENSMUSG00000062627 (Evidence)
Entrez Gene320713 (Evidence)
DFCITC1583031, TC1607154, TC1621412, TC1635059
DoTSDT.110841096, DT.91291963, DT.91329179, DT.94177524, DT.97364341, DT.99856314
NIA Mouse Gene IndexU042552
EC3.4.19.-
Consensus CDS ProjectCCDS18363.1
International Mouse Knockout Project StatusMysm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007999 VEGA Gene Model | MGI Sequence Detail 37061 C57BL/6J ±  kb
transcript OTTMUST00000018116 VEGA | MGI Sequence Detail 7420 Not Applicable 
polypeptide OTTMUSP00000008324 VEGA | MGI Sequence Detail 819 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(14) UniProt(1)
Polymorphisms
SNPs within 2kb(402 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009057 Homeodomain-like
InterPro IPR000555 JAB1/Mov34/MPN/PAD-1
InterPro IPR017930 Myb domain
InterPro IPR001005 SANT/Myb domain
InterPro IPR007526 SWIRM domain
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000010888 histone H2A deubiquitinase MYSM1
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:203809 Wang T, et al., The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation. Blood. 2013 Oct 17;122(16):2812-22
All references(37)
Other
accession IDs
MGI:2442057

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory