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Abi3bp Gene Detail
Summary
  • Symbol
    Abi3bp
  • Name
    ABI gene family, member 3 (NESH) binding protein
  • Synonyms
    5033411B22Rik, D930038M13Rik, eratin, TARSH
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444583
    NCBI Gene: 320712
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:56477878-56690135 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 34.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2948 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444583
protein coding gene Chr16:56477801-56690135 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022889
protein coding gene Chr16:55588769-55823669 (+)
A/J MGP_AJ_G0022856
protein coding gene Chr16:53201961-53420864 (+)
AKR/J MGP_AKRJ_G0022828
protein coding gene Chr16:54898354-55111188 (+)
BALB/cJ MGP_BALBcJ_G0022856
protein coding gene Chr16:53303515-53525239 (+)
C3H/HeJ MGP_C3HHeJ_G0022619
protein coding gene Chr16:55085656-55303242 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023304
protein coding gene Chr16:57174692-57411109 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020815
protein coding gene Chr16:52890206-53102012 (+)
CAST/EiJ MGP_CASTEiJ_G0022146
protein coding gene Chr16:55459625-55695235 (+)
CBA/J MGP_CBAJ_G0022592
protein coding gene Chr16:59459045-59699168 (+)
DBA/2J MGP_DBA2J_G0022724
protein coding gene Chr16:52966632-53181669 (+)
FVB/NJ MGP_FVBNJ_G0022699
protein coding gene Chr16:52730315-52947115 (+)
LP/J MGP_LPJ_G0022791
protein coding gene Chr16:55415366-55640283 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022717
protein coding gene Chr16:59772066-60027235 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023319
protein coding gene Chr16:55064151-55286145 (+)
PWK/PhJ MGP_PWKPhJ_G0021885
protein coding gene Chr16:53289286-53502875 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021715
protein coding gene Chr16:54803535-55033749 (+)
WSB/EiJ MGP_WSBEiJ_G0022190
protein coding gene Chr16:55081650-55307871 (+)



Homology
more
  • Human Ortholog
    ABI3BP, ABI family member 3 binding protein
  • Vertebrate Orthologs
    4
  • Human Ortholog
    ABI3BP, ABI family member 3 binding protein
    Orthology source: HGNC
  • Synonyms
    NESHBP, TARSH
  • Links
    NCBI Gene ID: 25890
    neXtProt AC: NX_Q7Z7G0
    UniProt: Q7Z7G0

  • Chr Location
    3q12.2; chr3:100749335-100993508 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035258 Ensembl Gene Model | MGI Sequence Detail 212258 C57BL/6J ±  kb
transcript ENSMUST00000231781 Ensembl | MGI Sequence Detail 5196 Not Applicable  
polypeptide ENSMUSP00000156096 Ensembl | MGI Sequence Detail 1637 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    13 Sequences
  • InterPro Domains
    IPR003961 Fibronectin type III
    IPR036116 Fibronectin type III superfamily
    IPR013783 Immunoglobulin-like fold
Molecular
Reagents
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  • All nucleic 28
    cDNA 28

    Microarray probesets 3
Other
Accession IDs
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MGI:2146450, MGI:2668157
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265820 Radder JE, et al., Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility. Am J Respir Cell Mol Biol. 2017 Sep;57(3):367-375

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory