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Kif20b Gene Detail
Summary
  • Symbol
    Kif20b
  • Name
    kinesin family member 20B
  • Synonyms
    33cex, C330014J10Rik, Kif20b, magoo, Mphosph1, N-6 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444576
    NCBI Gene: 240641
  • Gene Overview
    MyGene.info: KIF20B
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:34922361-34975745 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 29.79 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    357 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444576
protein coding gene Chr19:34922341-34975750 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025067
protein coding gene Chr19:33702331-33761723 (+)
A/J MGP_AJ_G0025043
protein coding gene Chr19:32070370-32128892 (+)
AKR/J MGP_AKRJ_G0025011
protein coding gene Chr19:33176587-33232566 (+)
BALB/cJ MGP_BALBcJ_G0025041
protein coding gene Chr19:32188341-32241656 (+)
C3H/HeJ MGP_C3HHeJ_G0024800
protein coding gene Chr19:33255712-33312655 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025482
protein coding gene Chr19:34704110-34762321 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022900
protein coding gene Chr19:31482165-31537472 (+)
CAST/EiJ MGP_CASTEiJ_G0024267
protein coding gene Chr19:33009508-33069691 (+)
CBA/J MGP_CBAJ_G0024777
protein coding gene Chr19:36325375-36383124 (+)
DBA/2J MGP_DBA2J_G0024909
protein coding gene Chr19:31965946-32019775 (+)
FVB/NJ MGP_FVBNJ_G0024870
protein coding gene Chr19:31793364-31846482 (+)
LP/J MGP_LPJ_G0024995
protein coding gene Chr19:33818405-33874976 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024901
protein coding gene Chr19:36083492-36161007 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025540
protein coding gene Chr19:33251561-33307461 (+)
PWK/PhJ MGP_PWKPhJ_G0024019
protein coding gene Chr19:31782732-31836898 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023819
protein coding gene Chr19:32121192-32178235 (+)
WSB/EiJ MGP_WSBEiJ_G0024334
protein coding gene Chr19:33327805-33384950 (+)



Homology
more
  • Human Ortholog
    KIF20B, kinesin family member 20B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KIF20B, kinesin family member 20B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT90, KRMP1, MPHOSPH1, MPP1, MPP-1
  • Links
    NCBI Gene ID: 9585
    neXtProt AC: NX_Q96Q89
    UniProt: Q96Q89

  • Chr Location
    10q23.31; chr10:89701590-89774943 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Kif20b mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    37 phenotypes from 3 alleles in 5 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for ENU induced mutations display craniofacial and nervous system abnormalities including exencephaly, microcephaly, decreased forebrain size and impaired neuronal progenitor proliferation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024795 Ensembl Gene Model | MGI Sequence Detail 53385 C57BL/6J ±  kb
    transcript ENSMUST00000087341 Ensembl | MGI Sequence Detail 5564 Not Applicable  
    polypeptide ENSMUSP00000084599 Ensembl | MGI Sequence Detail 1774 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 91
      cDNA 91

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2447029, MGI:3578175, MGI:4889064
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 9
      Phenotypes 13
    • Earliest
      J:70760 Miki H, et al., All kinesin superfamily protein, KIF, genes in mouse and human. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7004-11
    • Latest
      J:263533 Geister KA, et al., Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice. G3 (Bethesda). 2018 Feb 2;8(2):401-409

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory