About   Help   FAQ
Mbtps2
Gene Detail
Symbol

Name
ID
Mbtps2
membrane-bound transcription factor peptidase, site 2
MGI:2444506
Synonyms
9630032G22Rik, MGC:25655
Feature Type
protein coding gene
Genetic Map
Chromosome X
72.55 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:157535371-157598715 bp, - strand
From VEGA annotation of GRCm38

  63345 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9287  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MBTPS2
Protein SuperFamily: transcription factor yin and yang
Gene Tree: Mbtps2

Human
homologs
MBTPS2, membrane-bound transcription factor peptidase, site 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51360
neXtProt AC: NX_O43462

Human Synonyms: BRESEK, IFAP, KFSD, KFSDX, OLMSX, S2P

Human Chr (Location): Xp22.12-p22.11; chrX:21839538-21885423 (+)  GRCh38.p2

Disease Associations: (3) Diseases Associated with Human MBTPS2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(11) Targeted(2)
Incidental mutations (data from APF )
Interactions
Mbtps2 interacts with 345 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (64)    Tissues (34)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 64
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mbtps2 ; ZFIN mbtps2    NEW 
Molecular
reagents
All nucleic(12) cDNA(10) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000019403 (Evidence)
Ensembl Gene Model ENSMUSG00000046873 (Evidence)
Entrez Gene 270669 (Evidence)
DFCI TC1581144, TC1588555, TC1594957, TC1607116, TC1624701
Consensus CDS Project CCDS30498.1, CCDS30499.1
International Mouse Phenotyping Consortium Status Mbtps2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019403 VEGA Gene Model | MGI Sequence Detail 63345 C57BL/6J ±  kb
transcript OTTMUST00000046301 VEGA | MGI Sequence Detail 4797 Not Applicable 
polypeptide OTTMUSP00000020911 VEGA | MGI Sequence Detail 515 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(3)
Polymorphisms
SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000010230 membrane-bound transcription factor site-2 protease
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)
Other
accession IDs
MGI:2147907

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory