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Heatr3 Gene Detail
Summary
  • Symbol
    Heatr3
  • Name
    HEAT repeat containing 3
  • Synonyms
    C030036P15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444491
    NCBI Gene: 234549
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:88864483-88898655 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 43.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    914 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444491
 protein coding gene Chr8:88864453-88901656 (+)
129S1/SvImJ ENSMUSG00200016376
 protein coding gene Chr8:83221033-83255056 (+)
A/J ENSMUSG00195027688
 protein coding gene Chr8:83592556-83625132 (+)
AKR/J ENSMUSG00220034049
 protein coding gene Chr8:83620053-83654080 (+)
BALB/cJ ENSMUSG00180018288
 protein coding gene Chr8:83424613-83458636 (+)
C3H/HeJ ENSMUSG00175023643
 protein coding gene Chr8:83527954-83560514 (+)
C57BL/6NJ ENSMUSG00215014938
 protein coding gene Chr8:83131382-83165558 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031354
 protein coding gene Chr8:79676497-79714296 (+)
CAST/EiJ ENSTCUG00005016479
 protein coding gene Chr8:82988984-83022874 (+)
CBA/J ENSMUSG00210030029
 protein coding gene Chr8:83495926-83530122 (+)
DBA/2J ENSMUSG00185037790
 protein coding gene Chr8:89604508-89638701 (+)
FVB/NJ ENSMUSG00205013809
 protein coding gene Chr8:82551754-82585937 (+)
JF1/MsJ ENSUMUG00000027546
 protein coding gene Chr8:91927107-91959745 (+)
LP/J ENSMUSG00230025860
 protein coding gene Chr8:93217831-93251856 (+)
NOD/ShiLtJ ENSMUSG00190015432
 protein coding gene Chr8:83585281-83619303 (+)
NZO/HlLtJ ENSMUSG00225038555
 protein coding gene Chr8:96621827-96656023 (+)
PWK/PhJ ENSLUMG00010036842
 protein coding gene Chr8:83238067-83270718 (+)
SPRET/EiJ ENSMSPG00010027780
 protein coding gene Chr8:85169623-85202802 (+)
WSB/EiJ ENSIUOG00005019401
 protein coding gene Chr8:84309379-84343585 (+)



Homology
more
  • Human Ortholog
    HEATR3, HEAT repeat containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HEATR3, HEAT repeat containing 3
  • Synonyms
    DBA21, hsSyo1, SYO1
  • Links
    NCBI Gene ID: 55027
    UniProt: Q7Z4Q2

  • Chr Location
    16q12.1; chr16:50065964-50107272 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human HEATR3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    37 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    53
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031657 Ensembl Gene Model | MGI Sequence Detail 34173 C57BL/6J ±  kb
    transcript ENSMUST00000034079 Ensembl | MGI Sequence Detail 3251 Not Applicable  
    polypeptide ENSMUSP00000034079 Ensembl | MGI Sequence Detail 679 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 55
      cDNA 54
      Primer pair 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 59
      Gene Ontology 4
      Phenotypes 37
    • Earliest
      J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
    • Latest
      J:348117 Okuma H, et al., N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on alpha-dystroglycan and prevents muscular dystrophy. Elife. 2023 Feb 1;12
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory