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Manea Gene Detail
Summary
  • Symbol
    Manea
  • Name
    mannosidase, endo-alpha
  • Synonyms
    4932703L02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444484
    NCBI Gene: 242362
  • Gene Overview
    MyGene.info: MANEA
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:26324506-26346652 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 10.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    104 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444484
protein coding gene Chr4:26324506-26346891 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028105
protein coding gene Chr4:23447361-23469503 (-)
A/J MGP_AJ_G0028063
protein coding gene Chr4:22778331-22803056 (-)
AKR/J MGP_AKRJ_G0028028
protein coding gene Chr4:23299035-23321165 (-)
BALB/cJ MGP_BALBcJ_G0028074
protein coding gene Chr4:22846388-22868778 (-)
C3H/HeJ MGP_C3HHeJ_G0027804
protein coding gene Chr4:23472991-23496319 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028517
protein coding gene Chr4:24476742-24501364 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025859
protein coding gene Chr4:21096645-21119615 (-)
CAST/EiJ MGP_CASTEiJ_G0027259
protein coding gene Chr4:23137337-23162431 (-)
CBA/J MGP_CBAJ_G0027777
protein coding gene Chr4:25133536-25156204 (-)
DBA/2J MGP_DBA2J_G0027920
protein coding gene Chr4:22699067-22721520 (-)
FVB/NJ MGP_FVBNJ_G0027886
protein coding gene Chr4:22275454-22295371 (-)
LP/J MGP_LPJ_G0028029
protein coding gene Chr4:23566810-23593407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027919
protein coding gene Chr4:26867457-26907858 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028576
protein coding gene Chr4:23238317-23260474 (-)
PWK/PhJ MGP_PWKPhJ_G0026979
protein coding gene Chr4:22364801-22387682 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026807
protein coding gene Chr4:23029974-23051705 (-)
WSB/EiJ MGP_WSBEiJ_G0027336
protein coding gene Chr4:23211707-23236538 (-)



Homology
more
  • Human Ortholog
    MANEA, mannosidase endo-alpha
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MANEA, mannosidase endo-alpha
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ENDO, hEndo
  • Links
    NCBI Gene ID: 79694
    neXtProt AC: NX_Q5SRI9
    UniProt: Q5SRI9

  • Chr Location
    6q16.1; chr6:95577497-95609452 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11636
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MANEA
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 242362 NCBI Gene Model | MGI Sequence Detail 22147 C57BL/6J ±  kb
transcript NM_172865 RefSeq | MGI Sequence Detail 4645 C57BL/6  
polypeptide Q6NXH2 UniProt | EBI | MGI Sequence Detail 462 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory