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Cass4 Gene Detail
Summary
  • Symbol
    Cass4
  • Name
    Cas scaffolding protein family member 4
  • Synonyms
    F730031O20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444482
    NCBI Gene: 320664
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:172393794-172433757 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 94.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    342 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444482
protein coding gene Chr2:172393794-172433757 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026944
protein coding gene Chr2:178566630-178606089 (+)
A/J MGP_AJ_G0026911
protein coding gene Chr2:171088017-171128685 (+)
AKR/J MGP_AKRJ_G0026882
protein coding gene Chr2:176250181-176297011 (+)
BALB/cJ MGP_BALBcJ_G0026920
protein coding gene Chr2:171478414-171518891 (+)
C3H/HeJ MGP_C3HHeJ_G0026662
protein coding gene Chr2:176605006-176646817 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027367
protein coding gene Chr2:183730753-183773421 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024737
protein coding gene Chr2:164336651-164376710 (+)
CAST/EiJ MGP_CASTEiJ_G0026120
protein coding gene Chr2:177268335-177318549 (+)
CBA/J MGP_CBAJ_G0026639
protein coding gene Chr2:190587208-190632107 (+)
DBA/2J MGP_DBA2J_G0026777
protein coding gene Chr2:170183225-170223394 (+)
FVB/NJ MGP_FVBNJ_G0026743
protein coding gene Chr2:168780830-168825067 (+)
LP/J MGP_LPJ_G0026878
protein coding gene Chr2:178496043-178538017 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026762
protein coding gene Chr2:193574583-193618700 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027424
protein coding gene Chr2:176216261-176263250 (+)
PWK/PhJ MGP_PWKPhJ_G0025857
protein coding gene Chr2:169937618-169982616 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025657
protein coding gene Chr2:175218592-175261405 (+)
WSB/EiJ MGP_WSBEiJ_G0026193
protein coding gene Chr2:177190649-177236597 (+)



Homology
more
  • Human Ortholog
    CASS4, Cas scaffold protein family member 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CASS4, Cas scaffold protein family member 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf32, CAS4, HEFL, HEPL
  • Links
    NCBI Gene ID: 57091
    neXtProt AC: NX_Q9NQ75
    UniProt: Q9NQ75

  • Chr Location
    20q13.31; chr20:56411550-56460240 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 75128
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CASS4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320664 NCBI Gene Model | MGI Sequence Detail 39964 C57BL/6J ±  kb
transcript NM_001080820 RefSeq | MGI Sequence Detail 3705 C57BL/6  
polypeptide Q08EC4 UniProt | EBI | MGI Sequence Detail 804 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory