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Cass4 Gene Detail
Summary
  • Symbol
    Cass4
  • Name
    Cas scaffolding protein family member 4
  • Synonyms
    F730031O20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444482
    NCBI Gene: 320664
Location & Maps
more
  • Sequence Map
    Chr2:172393794-172433757 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      39964 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 94.85 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CASS4, Cas scaffolding protein family member 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CASS4, Cas scaffolding protein family member 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C20orf32, CAS4, HEFL, HEPL
  • Links
    NCBI Gene ID: 57091
    neXtProt AC: NX_Q9NQ75

  • Chr Location
    20q13.31; chr20:56411548-56459340 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 75128
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CASS4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016152 VEGA Gene Model | MGI Sequence Detail 39964 C57BL/6J ±  kb
transcript OTTMUST00000088926 VEGA | MGI Sequence Detail 2702 Not Applicable  
polypeptide OTTMUSP00000048534 VEGA | MGI Sequence Detail 804 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    342 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005059 cas scaffolding protein family member 4
  • InterPro Domains
    IPR021901 CAS family, DUF3513
    IPR014928 Serine rich protein interaction
    IPR001452 SH3 domain
Molecular
Reagents
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  • All nucleic 10
    cDNA 9
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory