About   Help   FAQ
Pomt2 Gene Detail
Summary
  • Symbol
    Pomt2
  • Name
    protein-O-mannosyltransferase 2
  • Synonyms
    A830009D15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444430
    NCBI Gene: 217734
  • Gene Overview
    MyGene.info: POMT2
Location & Maps
more
  • Sequence Map
    Chr12:87106866-87147902 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      41037 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 41.30 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    POMT2, protein O-mannosyltransferase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    POMT2, protein O-mannosyltransferase 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LGMD2N, MDDGA2, MDDGB2, MDDGC2
  • Links
    NCBI Gene ID: 29954
    neXtProt AC: NX_Q9UKY4

  • Chr Location
    14q24; chr14:77274956-77320884 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5297
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: POMT2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 3 alleles in 5 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    6
  • Genomic Mutations
    1 involving Pomt2
  • Incidental Mutations
Mice homozygous for one knock-out allele die between E8.5 and E9.5 with abnormal Reichert's membrane and runting. Mice homozygous for another allele die before implantation and arrest at the morula stage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034126 Ensembl Gene Model | MGI Sequence Detail 41037 C57BL/6J ±  kb
transcript ENSMUST00000037788 Ensembl | MGI Sequence Detail 5059 Not Applicable  
polypeptide ENSMUSP00000035260 Ensembl | MGI Sequence Detail 820 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    127 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    cDNA 44
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144992
References
more
  • Summaries
    All 33
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:215959 Yagi H, et al., AGO61-dependent GlcNAc modification primes the formation of functional glycans on alpha-dystroglycan. Sci Rep. 2013;3:3288

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory