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Pomt2
Gene Detail
Symbol

Name
ID
Pomt2
protein-O-mannosyltransferase 2
MGI:2444430
Synonyms
A830009D15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 12
41.30 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:87106866-87147902 bp, - strand
From NCBI annotation of GRCm38

  41037 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5297  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pomt2

Human
homologs
Human Homolog POMT2, protein-O-mannosyltransferase 2
NCBI Gene ID 29954
neXtProt AC  NX_Q9UKY4
Human Synonyms  LGMD2N, MDDGA2, MDDGB2, MDDGC2
Human Chr (Location)  14q24; chr14:77274956-77320882 (-)  GRCh38
Disease Associations  (4) Diseases Associated with Human POMT2
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for one knock-out allele die between E8.5 and E9.5 with abnormal Reichert's membrane and runting. Mice homozygous for another allele die before implantation and arrest at the morula stage.
 
Interactions
Pomt2 interacts with 283 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (204)    Tissues (124)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 15
RNA in situ 176
Northern blot 4
Western blot 4
RT-PCR 5
cDNA source data(43)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) cDNA(44) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000034126 (Evidence)
Entrez Gene217734 (Evidence)
UniGene388249
DFCITC1576190, TC1686628, TC1727276
NIA Mouse Gene IndexU034206
EC2.4.1.109
Consensus CDS ProjectCCDS26070.1
International Mouse Knockout Project StatusPomt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 217734 NCBI Gene Model | MGI Sequence Detail 41037 C57BL/6J ±  kb
transcript NM_153415 RefSeq | MGI Sequence Detail 5059 C57BL/6 
polypeptide Q8BGQ4 UniProt | EBI | MGI Sequence Detail 820 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(128 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027005 Glycosyltransferase 39 like
InterPro IPR003342 Glycosyl transferase, family 39
InterPro IPR016093 MIR motif
Protein Ontology PR:000013019 protein O-mannosyl-transferase 2
Graphical View of Protein Domain Structure
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:205502 Lommel M, et al., Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21024-9
All references(36)
Other
accession IDs
MGI:2144992

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory