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Snrnp200
Gene Detail
 Symbol
Name
ID
Snrnp200
small nuclear ribonucleoprotein 200 (U5)
MGI:2444401
Synonyms A330064G03Rik, Ascc3l1, HELIC2, U5-200KD
Feature Type protein coding gene
Genetic Map
Chromosome 2
61.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:127208386-127240451 bp, + strand
From VEGA annotation of GRCm38

  32066 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5859  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: helicase, BRR2 type
Gene Tree: Snrnp200

Human
homologs
Human Homolog SNRNP200, small nuclear ribonucleoprotein 200kDa (U5)
NCBI Gene ID 23020
neXtProt AC  NX_O75643
Human Synonyms  ASCC3L1, BRR2, HELIC2, RP33, U5-200KD
Human Chr (Location)  2q11.2; chr2:96274336-96305569 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SNRNP200
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(8) Targeted(3) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality before implantation.
 
Interactions
Snrnp200 interacts with 117 markers (Mir10a, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process ATP catabolic process, mRNA processing, ...
Component catalytic step 2 spliceosome, membrane, ...
Function ATP binding, ATP-dependent helicase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (22)    Images (4)
Theiler Stages: 21, 28
Assay TypeResults
RNA in situ 20
RT-PCR 2
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016015 (Evidence)
Ensembl Gene ModelENSMUSG00000003660 (Evidence)
Entrez Gene320632 (Evidence)
EC3.6.4.13
Consensus CDS ProjectCCDS16695.1
International Mouse Knockout Project StatusSnrnp200
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016015 VEGA Gene Model | MGI Sequence Detail 32066 C57BL/6J ±  kb
transcript OTTMUST00000038159 VEGA | MGI Sequence Detail 6745 Not Applicable 
polypeptide OTTMUSP00000017113 VEGA | MGI Sequence Detail 2136 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(416 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR004179 Sec63 domain
Protein Ontology PR:000015332 U5 small nuclear ribonucleoprotein 200 kDa helicase
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:103446 McKee AE, et al., A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
All references(30)
Other
accession IDs
MGI:2679724

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory