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Snrnp200
Gene Detail
Symbol

Name
ID
Snrnp200
small nuclear ribonucleoprotein 200 (U5)
MGI:2444401
Synonyms
A330064G03Rik, Ascc3l1, HELIC2, U5-200KD
Feature Type
protein coding gene
Genetic Map
Chromosome 2
61.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:127208386-127240451 bp, + strand
From VEGA annotation of GRCm38

  32066 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5859  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SNRNP200
Protein SuperFamily: helicase, BRR2 type
Gene Tree: Snrnp200

Human
homologs
SNRNP200, small nuclear ribonucleoprotein 200kDa (U5)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23020
neXtProt AC: NX_O75643

Human Synonyms: ASCC3L1, BRR2, HELIC2, RP33, U5-200KD

Human Chr (Location): 2q11.2; chr2:96274336-96305569 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SNRNP200

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(8) Targeted(3) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality before implantation.
 
Interactions
Snrnp200 interacts with 117 markers (Mir10a, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process mRNA processing, mRNA splicing, via spliceosome, ...
Component catalytic step 2 spliceosome, membrane, ...
Function ATP binding, ATP-dependent helicase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (22)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 20
RT-PCR 2
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase snrnp200    NEW 
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000016015 (Evidence)
Ensembl Gene Model ENSMUSG00000003660 (Evidence)
Entrez Gene 320632 (Evidence)
EC 3.6.4.13
Consensus CDS Project CCDS16695.1
International Mouse Phenotyping Consortium Status Snrnp200
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016015 VEGA Gene Model | MGI Sequence Detail 32066 C57BL/6J ±  kb
transcript OTTMUST00000038159 VEGA | MGI Sequence Detail 6745 Not Applicable 
polypeptide OTTMUSP00000017113 VEGA | MGI Sequence Detail 2136 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(416 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR000008 C2 domain
InterPro IPR011545 DEAD/DEAH box helicase domain
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase superfamily 1/2, ATP-binding domain
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR004179 Sec63 domain
Protein Ontology PR:000015332 U5 small nuclear ribonucleoprotein 200 kDa helicase
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:103446 McKee AE, et al., A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
All references(29)
Other
accession IDs
MGI:2679724

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory