Snrnp200
Gene Detail

Symbol Name ID

Snrnp200 small nuclear ribonucleoprotein 200 (U5) MGI:2444401

Synonyms

A330064G03Rik, Ascc3l1, HELIC2, U5-200KD

Feature Type

protein coding gene

Genetic Map

Chromosome 2

61.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr2:127208386-127240451 bp, + strand From VEGA annotation of GRCm38   32066 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5859  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Snrnp200

Human homologs

Human Homolog		SNRNP200, small nuclear ribonucleoprotein 200kDa (U5)
NCBI Gene ID		23020
neXtProt AC		NX_O75643
Human Synonyms		ASCC3L1, BRR2, HELIC2, RP33, U5-200KD
Human Chr (Location)		2q11.2; chr2:96940074-96971307 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SNRNP200

Alleles and phenotypes

All alleles(11) : Targeted(2) Gene trapped(8) Transgenic(1)
 

Mice homozygous for a transgenic gene disruption exhibit embryonic lethality before implantation.

 

Gene Ontology (GO) classifications

All GO classifications: (20 annotations)

Process	metabolic process, mRNA processing, ...
Component	catalytic step 2 spliceosome, nucleus, ...
Function	ATP binding, ATP-dependent helicase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (22)    Images (4)
Theiler Stages: 21, 28

Assay Type	Results
RNA in situ	20
RT-PCR	2

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000016015 (Evidence)
Ensembl Gene Model	ENSMUSG00000003660 (Evidence)
Entrez Gene	320632 (Evidence)
EC	3.6.4.13
Consensus CDS Project	CCDS16695.1
International Mouse Knockout Project Status	Snrnp200

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016015	VEGA Gene Model | MGI Sequence Detail	32066	C57BL/6J
transcript	OTTMUST00000038159	VEGA | MGI Sequence Detail	6745	Not Applicable
polypeptide	OTTMUSP00000017113	VEGA | MGI Sequence Detail	2136	Not Applicable

All sequences(33) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(243 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003593	AAA+ ATPase domain
InterPro	IPR011545	DNA/RNA helicase, DEAD/DEAH box type, N-terminal
InterPro	IPR001650	Helicase, C-terminal
InterPro	IPR014001	Helicase, superfamily 1/2, ATP-binding domain
InterPro	IPR027417	P-loop containing nucleoside triphosphate hydrolase
InterPro	IPR004179	Sec63 domain
Protein Ontology	PR:000015332	U5 small nuclear ribonucleoprotein 200 kDa helicase

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:103446 McKee AE, et al., A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
All references(28)

Other accession IDs

MGI:2679724