About   Help   FAQ
Fat3
Gene Detail
 Symbol
Name
ID
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
MGI:2444314
Synonyms 9430076A06Rik, D430038H04Rik, LOC234973, LOC382129
Feature Type protein coding gene
Genetic Map
Chromosome 9
5.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:15910205-16378231 bp, - strand
From Ensembl annotation of GRCm38

  468027 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:82252  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Fat3

Human
homologs
Human Homolog FAT3, FAT atypical cadherin 3
NCBI Gene ID 120114
neXtProt AC  NX_Q8TDW7
Human Synonyms  CDHF15, CDHR10
Human Chr (Location)  11q14.3; chr11:92225112-92896470 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozgyous for a knock-out allele exhibit abnormal amacrine cell differentiation and migration that result in the formation of two additional plexiform layers and thickened retinal ganglion layer.
 
Interactions
Fat3 interacts with 538 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell adhesion, cell morphogenesis involved in differentiation, ...
Component dendrite, integral component of membrane, ...
Function calcium ion binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (448)    Tissues (104)    Images (86)
Theiler Stages: 19, 20, 22, 23, 25, 28
Assay TypeResults
Immunohistochemistry 42
RNA in situ 368
Western blot 28
RT-PCR 10
cDNA source data(45)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(45) Primer pair(3) Other(1)
Microarray probesets(15)
Other database
links
Ensembl Gene ModelENSMUSG00000074505 (Evidence)
Entrez Gene270120 (Evidence)
UniGene195010
DFCITC1621215, TC1622859, TC1668589
DoTSDT.87040122, DT.94134817, DT.94270330
Consensus CDS ProjectCCDS40539.1
International Mouse Knockout Project StatusFat3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074505 Ensembl Gene Model | MGI Sequence Detail 468027 C57BL/6J ±  kb
transcript ENSMUST00000082170 Ensembl | MGI Sequence Detail 18456 Not Applicable 
polypeptide ENSMUSP00000080808 Ensembl | MGI Sequence Detail 4551 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(12) UniProt(2)
Polymorphisms SNPs within 2kb(2333 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2335)
Protein-related
information
ResourceIDDescription
InterPro IPR002126 Cadherin
InterPro IPR020894 Cadherin conserved site
InterPro IPR015919 Cadherin-like
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR001881 EGF-like calcium-binding
InterPro IPR018097 EGF-like calcium-binding, conserved site
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000152 EGF-type aspartate/asparagine hydroxylation site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR001791 Laminin G domain
Protein Ontology PR:000007352 protocadherin Fat 3
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:196080 Elsen GE, et al., The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
All references(26)
Other
accession IDs
MGI:2685356, MGI:2685978, MGI:3036241

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory