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Serinc5 Gene Detail
Summary
  • Symbol
    Serinc5
  • Name
    serine incorporator 5
  • Synonyms
    A130038L21Rik, AIGP3, TPO1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444223
    NCBI Gene: 218442
Location & Maps
more
  • Sequence Map
    Chr13:92611138-92711944 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      100807 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SERINC5, serine incorporator 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SERINC5, serine incorporator 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C5orf12, TPO1
  • Links
    NCBI Gene ID: 256987
    neXtProt AC: NX_Q86VE9

  • Chr Location
    5q14.1; chr5:80111227-80256082 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    2
  • Genomic Mutations
    1 involving Serinc5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021703 Ensembl Gene Model | MGI Sequence Detail 100807 C57BL/6J ±  kb
transcript ENSMUST00000049488 Ensembl | MGI Sequence Detail 5316 Not Applicable  
polypeptide ENSMUSP00000047547 Ensembl | MGI Sequence Detail 461 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    807 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000014675 serine incorporator 5
  • InterPro Domains
    IPR029555 Serine incorporator 5
    IPR005016 Serine incorporator/TMS membrane protein
Molecular
Reagents
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  • All nucleic 130
    cDNA 129
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory