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Vps13c Gene Detail
Summary
  • Symbol
    Vps13c
  • Name
    vacuolar protein sorting 13C
  • Synonyms
    C230055H22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444207
    NCBI Gene: 320528
Location & Maps
more
  • Sequence Map
    Chr9:67840396-67995634 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      155239 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 36.77 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    VPS13C, vacuolar protein sorting 13 homolog C
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VPS13C, vacuolar protein sorting 13 homolog C
    Orthology source: HomoloGene
  • Synonyms
    PARK23
  • Links
    NCBI Gene ID: 54832
    neXtProt AC: NX_Q709C8

  • Chr Location
    15q22.2; chr15:61852389-62060465 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human VPS13C associations

Human Disease Mouse Models
       Parkinson Disease 23, Autosomal Recessive Early-Onset; PARK23   OMIM: 616840
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Gene trapped
    10
  • Targeted
    3
  • Genomic Mutations
    1 involving Vps13c
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035284 Ensembl Gene Model | MGI Sequence Detail 155239 C57BL/6J ±  kb
transcript ENSMUST00000077879 Ensembl | MGI Sequence Detail 11523 Not Applicable  
polypeptide ENSMUSP00000077040 Ensembl | MGI Sequence Detail 3748 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    856 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000017321 vacuolar protein sorting-associated protein 13C
  • InterPro Domains
    IPR015412 Autophagy-related, C-terminal
    IPR026847 Vacuolar protein sorting-associated protein 13
    IPR031645 Vacuolar protein sorting-associated protein 13, C-terminal
    IPR026854 Vacuolar protein sorting-associated protein 13, N-terminal domain
    IPR031646 Vacuolar protein sorting-associated protein 13, second N-terminal domain
    IPR009543 Vacuolar protein sorting-associated protein 13, SHR-binding domain
    IPR031642 VPS13, repeated coiled region
Molecular
Reagents
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  • All nucleic 12
    Genomic 1
    cDNA 10
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
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MGI:2143091, MGI:2143255, MGI:2143453
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:221584 Quesnel-Vallieres M, et al., Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory