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Dgkh Gene Detail
Summary
  • Symbol
    Dgkh
  • Name
    diacylglycerol kinase, eta
  • Synonyms
    5930402B05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444188
    NCBI Gene: 380921
Location & Maps
more
  • Sequence Map
    Chr14:78569609-78725089 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      155481 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 41.56 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DGKH, diacylglycerol kinase eta
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DGKH, diacylglycerol kinase eta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DGKeta
  • Links
    NCBI Gene ID: 160851
    neXtProt AC: NX_Q86XP1

  • Chr Location
    13q14.11; chr13:42040036-42256584 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 99373
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: DGKH
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    11
  • Targeted
    2
  • Genomic Mutations
    1 involving Dgkh
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034731 Ensembl Gene Model | MGI Sequence Detail 155481 C57BL/6J ±  kb
transcript ENSMUST00000074729 Ensembl | MGI Sequence Detail 3967 Not Applicable  
polypeptide ENSMUSP00000074290 Ensembl | MGI Sequence Detail 1156 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1564 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR000756 Diacylglycerol kinase, accessory domain
    IPR001206 Diacylglycerol kinase, catalytic domain
    IPR016064 NAD kinase/diacylglycerol kinase-like domain
    IPR011993 PH domain-like
    IPR001849 Pleckstrin homology domain
    IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
    IPR001660 Sterile alpha motif domain
    IPR013761 Sterile alpha motif/pointed domain
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:233777 Ray JP, et al., The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. 2015 Oct 20;43(4):690-702

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory