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Tanc2 Gene Detail
Summary
  • Symbol
    Tanc2
  • Name
    tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
  • Synonyms
    3526402J09Rik, 5730590C14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444121
    NCBI Gene: 77097
Location & Maps
more
  • Sequence Map
    Chr11:105589986-105929304 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      339319 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.73 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    rols, ROLSA
  • Links
    NCBI Gene ID: 26115
    neXtProt AC: NX_Q9HCD6

  • Chr Location
    17q23.3; chr17:62966664-63427706 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 64680
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: TANC2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap vector die prior to E12.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002986 VEGA Gene Model | MGI Sequence Detail 339319 C57BL/6J ±  kb
transcript OTTMUST00000006113 VEGA | MGI Sequence Detail 11855 Not Applicable  
polypeptide OTTMUSP00000003018 VEGA | MGI Sequence Detail 1994 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    865 from dbSNP Build 142
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000016047 protein TANC2
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR020683 Ankyrin repeat-containing domain
    IPR023114 Elongated TPR repeat-containing domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR011990 Tetratricopeptide-like helical domain
    IPR019734 Tetratricopeptide repeat
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
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  • All nucleic 112
    cDNA 112

    Microarray probesets 4
Other
Accession IDs
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MGI:1924347
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory