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Vwc2l Gene Detail
Summary
  • Symbol
    Vwc2l
  • Name
    von Willebrand factor C domain-containing protein 2-like
  • Synonyms
    A830006F12Rik, Brl, brorin-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444069
    NCBI Gene: 320460
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:70725715-70885397 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 35.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    934 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444069
protein coding gene Chr1:70725221-70888938 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016123
protein coding gene Chr1:71128818-71300394 (+)
A/J MGP_AJ_G0016106
protein coding gene Chr1:68611129-68765324 (+)
AKR/J MGP_AKRJ_G0016063
protein coding gene Chr1:70596956-70757873 (+)
BALB/cJ MGP_BALBcJ_G0016061
protein coding gene Chr1:68730058-68892041 (+)
C3H/HeJ MGP_C3HHeJ_G0015892
protein coding gene Chr1:70919571-71086241 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016514
protein coding gene Chr1:73859413-74036426 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014235
protein coding gene Chr1:64345211-64501874 (+)
CAST/EiJ MGP_CASTEiJ_G0015476
protein coding gene Chr1:70159718-70318728 (+)
CBA/J MGP_CBAJ_G0015865
protein coding gene Chr1:76327588-76514656 (+)
DBA/2J MGP_DBA2J_G0015966
protein coding gene Chr1:68017028-68175326 (+)
FVB/NJ MGP_FVBNJ_G0015969
protein coding gene Chr1:67196263-67352910 (+)
LP/J MGP_LPJ_G0016038
protein coding gene Chr1:72186964-72351510 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015989
protein coding gene Chr1:79838477-80017168 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016561
protein coding gene Chr1:70571378-70735641 (+)
PWK/PhJ MGP_PWKPhJ_G0015263
protein coding gene Chr1:67419142-67580701 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015042
protein coding gene Chr1:69981100-70153039 (+)
WSB/EiJ MGP_WSBEiJ_G0015538
protein coding gene Chr1:70384296-70547030 (+)



Homology
more
  • Human Ortholog
    VWC2L, von Willebrand factor C domain containing 2 like
  • Vertebrate Orthologs
    9
  • Human Ortholog
    VWC2L, von Willebrand factor C domain containing 2 like
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 402117
    neXtProt AC: NX_B2RUY7
    UniProt: B2RUY7

  • Chr Location
    2q34-q35; chr2:214411737-214575929 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 27945
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: VWC2L
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045648 Ensembl Gene Model | MGI Sequence Detail 159683 C57BL/6J ±  kb
transcript ENSMUST00000053922 Ensembl | MGI Sequence Detail 4655 Not Applicable  
polypeptide ENSMUSP00000058142 Ensembl | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:188364 Schwenk J, et al., High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron. 2012 May 24;74(4):621-33

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory