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Slc66a3 Gene Detail
Summary
  • Symbol
    Slc66a3
  • Name
    solute carrier family 66 member 3
  • Synonyms
    E030024M05Rik, Pqlc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444067
    NCBI Gene: 217430
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:17038649-17050385 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 8.04 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    317 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444067
 protein coding gene Chr12:17038649-17050409 (-)
129S1/SvImJ ENSMUSG00200022111
 protein coding gene Chr12:14072704-14092111 (-)
A/J ENSMUSG00195016181
 protein coding gene Chr12:14084682-14104091 (-)
AKR/J ENSMUSG00220024867
 protein coding gene Chr12:14169246-14188646 (-)
BALB/cJ ENSMUSG00180008452
 protein coding gene Chr12:14063317-14082727 (-)
C3H/HeJ ENSMUSG00175005734
 protein coding gene Chr12:14094596-14114027 (-)
C57BL/6NJ ENSMUSG00215005269
 protein coding gene Chr12:13865853-13885284 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017631
 protein coding gene Chr12:13400349-13412331 (-)
CAST/EiJ ENSTCUG00005005608
 protein coding gene Chr12:13590850-13602616 (-)
CBA/J ENSMUSG00210007456
 protein coding gene Chr12:14106454-14125885 (-)
DBA/2J ENSMUSG00185003357
 protein coding gene Chr12:14019298-14038705 (-)
FVB/NJ ENSMUSG00205001374
 protein coding gene Chr12:13971764-13991174 (-)
JF1/MsJ ENSUMUG00000007827
 protein coding gene Chr12:13937246-13956676 (-)
LP/J ENSMUSG00230020933
 protein coding gene Chr12:15841551-15860989 (-)
NOD/ShiLtJ ENSMUSG00190012673
 protein coding gene Chr12:15301475-15320906 (-)
NZO/HlLtJ ENSMUSG00225029889
 protein coding gene Chr12:17944360-17963767 (-)
PWK/PhJ ENSLUMG00010003978
 protein coding gene Chr12:13711447-13730861 (-)
SPRET/EiJ ENSMSPG00010002795
 protein coding gene Chr12:14697023-14708707 (-)
WSB/EiJ ENSIUOG00005001470
 protein coding gene Chr12:14084732-14104161 (-)



Homology
more
  • Human Ortholog
    SLC66A3, solute carrier family 66 member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC66A3, solute carrier family 66 member 3
  • Synonyms
    C2orf22, PQLC3
  • Links
    NCBI Gene ID: 130814
    UniProt: Q8N755

  • Chr Location
    2p25.1; chr2:11155198-11178870 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    4
  • cDNA Data
    24
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217430 NCBI Gene Model | MGI Sequence Detail 11737 C57BL/6J ±  kb
transcript NM_172574 RefSeq | MGI Sequence Detail 1928 C57BL/6  
polypeptide Q8C6U2 UniProt | EBI | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 24
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145089, MGI:7414082
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory