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Tmprss11g
Gene Detail
Symbol

Name
ID
Tmprss11g
transmembrane protease, serine 11g
MGI:2444058
Synonyms
9930032O22Rik, Desc4
Feature Type
protein coding gene
Genetic Map
Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:86485876-86518600 bp, - strand
From VEGA annotation of GRCm38

  32725 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:82239  Vertebrate Homology Class
1 mouse; 1 rat; 1 cattle; 1 dog

HCOP human homology predictions: TMPRSS11GP
Protein SuperFamily: transmembrane serine protease, TMPRSS11A type
Gene Tree: Tmprss11g

Human
homologs
TMPRSS11GP, transmembrane protease, serine 11G, pseudogene
Orthology source: HGNC

IDs:
NCBI Gene ID: 644759

Human Chr (Location): 4q13.2; chr4:67991812-67997439 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Tmprss11g interacts with 239 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process proteolysis
Component extracellular region, integral component of membrane, ...
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000033619 (Evidence)
Ensembl Gene Model ENSMUSG00000079451 (Evidence)
Entrez Gene 320454 (Evidence)
DFCI TC1589374
DoTS DT.91298680
NIA Mouse Gene Index U026350
EC 3.4.21.-
Consensus CDS Project CCDS51532.1
International Mouse Phenotyping Consortium Status Tmprss11g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033619 VEGA Gene Model | MGI Sequence Detail 32725 C57BL/6J ±  kb
transcript OTTMUST00000084708 VEGA | MGI Sequence Detail 2873 Not Applicable 
polypeptide OTTMUSP00000045687 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(249 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR017329 Peptidase S1A, HAT/DESC1
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR000082 SEA domain
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000006843 serine protease DESC4
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:175364 Sales KU, et al., Expression and Genetic Loss of Function Analysis of the HAT/DESC Cluster Proteases TMPRSS11A and HAT. PLoS One. 2011;6(8):e23261
All references(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory