About   Help   FAQ
Tmprss11g Gene Detail
Summary
  • Symbol
    Tmprss11g
  • Name
    transmembrane protease, serine 11g
  • Synonyms
    9930032O22Rik, Desc4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444058
    NCBI Gene: 320454
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:86485877-86518600 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    246 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444058
protein coding gene Chr5:86485876-86518600 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029670
protein coding gene Chr5:87328980-87367480 (-)
A/J MGP_AJ_G0029638
protein coding gene Chr5:83758141-83789448 (-)
AKR/J MGP_AKRJ_G0029586
protein coding gene Chr5:86540774-86576847 (-)
BALB/cJ MGP_BALBcJ_G0029647
protein coding gene Chr5:84661340-84693158 (-)
C3H/HeJ MGP_C3HHeJ_G0029370
protein coding gene Chr5:87014548-87046094 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030101
protein coding gene Chr5:90943431-90974796 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027343
protein coding gene Chr5:79577670-79611863 (-)
CAST/EiJ MGP_CASTEiJ_G0028778
protein coding gene Chr5:86310929-86346272 (-)
CBA/J MGP_CBAJ_G0029339
protein coding gene Chr5:93852379-93883655 (-)
DBA/2J MGP_DBA2J_G0029484
protein coding gene Chr5:83954430-83986625 (-)
FVB/NJ MGP_FVBNJ_G0029445
protein coding gene Chr5:82874126-82905453 (-)
LP/J MGP_LPJ_G0029571
protein coding gene Chr5:87735169-87767413 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029473
protein coding gene Chr5:98704695-98738577 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030134
protein coding gene Chr5:86107889-86139788 (-)
PWK/PhJ MGP_PWKPhJ_G0028502
protein coding gene Chr5:82914417-82947593 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028335
protein coding gene Chr5:85455267-85494787 (-)
WSB/EiJ MGP_WSBEiJ_G0028859
protein coding gene Chr5:86470750-86502862 (-)



Homology
more
  • Human Ortholog
    TMPRSS11GP, transmembrane serine protease 11G, pseudogene
  • Vertebrate Orthologs
    4
  • Human Ortholog
    TMPRSS11GP, transmembrane serine protease 11G, pseudogene
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 644759

  • Chr Location
    4q13.2; chr4:67991812-67997439 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    8 phenotype references
Mice homozygous for a null allele in combination with other Tmprss11 null alleles are normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320454 NCBI Gene Model | MGI Sequence Detail 32724 C57BL/6J ±  kb
transcript NM_177162 RefSeq | MGI Sequence Detail 2872 C57BL/6  
polypeptide Q8BZ10 UniProt | EBI | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:279596 Callies LK, et al., Iterative, multiplexed CRISPR-mediated gene editing for functional analysis of complex protease gene clusters. J Biol Chem. 2019 Sep 9;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/11/2020
MGI 6.14
The Jackson Laboratory