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Alg6
Gene Detail
Symbol

Name
ID
Alg6
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
MGI:2444031
Synonyms
E230028F23Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
45.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:99715664-99763460 bp, + strand
From VEGA annotation of GRCm38

  47797 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6920  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ALG6
Protein SuperFamily: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase/dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Gene Tree: Alg6

Human
homologs
ALG6, ALG6, alpha-1,3-glucosyltransferase
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 29929
neXtProt AC: NX_Q9Y672

Human Synonyms: CDG1C

Human Chr (Location): 1p31.3; chr1:63367590-63438562 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ALG6

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(12) Targeted(3)
Genomic Mutations involving Alg6 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Alg6 interacts with 227 markers (Mir7-1, Mir7-2, Mir7b, ...)
Expression
Literature Summary: (2 records)
Data Summary: Results (96)    Tissues (95)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
RT-PCR 2
cDNA source data(29)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase alg6 ; ZFIN alg6    NEW 
Molecular
reagents
All nucleic(31) cDNA(29) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000007982 (Evidence)
Ensembl Gene Model ENSMUSG00000073792 (Evidence)
Entrez Gene 320438 (Evidence)
UniGene 32408
DFCI TC1647306, TC1609330, TC1697634, TC1641503, TC1602658
DoTS DT.91417301, DT.94170138, DT.94191045, DT.99851157, DT.94288937
NIA Mouse Gene Index U004534
EC 2.4.1.267
Consensus CDS Project CCDS38818.1
International Mouse Phenotyping Consortium Status Alg6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007982 VEGA Gene Model | MGI Sequence Detail 47797 C57BL/6J ±  kb
transcript OTTMUST00000018089 VEGA | MGI Sequence Detail 3079 Not Applicable 
polypeptide OTTMUSP00000008309 VEGA | MGI Sequence Detail 507 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(22) UniProt(3)
Polymorphisms
SNPs within 2kb(225 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004856 Glycosyl transferase, ALG6/ALG8
Protein Ontology PR:000003946 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173488 Pandey P, et al., Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease. BMC Syst Biol. 2011;5:56
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory