About   Help   FAQ
Alg6
Gene Detail
 Symbol
Name
ID
Alg6
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
MGI:2444031
Synonyms E230028F23Rik
Feature Type protein coding gene
Genetic Map
Chromosome 4
45.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:99715664-99763460 bp, + strand
From VEGA annotation of GRCm38

  47797 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6920  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase/dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Gene Tree: Alg6

Human
homologs
Human Homolog ALG6, ALG6, alpha-1,3-glucosyltransferase
NCBI Gene ID 29929
neXtProt AC  NX_Q9Y672
Human Synonyms  CDG1C
Human Chr (Location)  1p31.3; chr1:63367590-63438562 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALG6
Alleles
and
phenotypes
All alleles(14) : Gene trapped(12) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process protein N-linked glycosylation
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function glucosyltransferase activity, transferase activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (96)    Tissues (95)    Images (1)
Theiler Stages: 22, 25
Assay TypeResults
RNA in situ 94
RT-PCR 2
cDNA source data(29)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(31) cDNA(29) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000007982 (Evidence)
Ensembl Gene ModelENSMUSG00000073792 (Evidence)
Entrez Gene320438 (Evidence)
UniGene32408
DFCITC1602658, TC1609330, TC1641503, TC1647306, TC1697634
DoTSDT.91417301, DT.94170138, DT.94191045, DT.94288937, DT.99851157
NIA Mouse Gene IndexU004534
EC2.4.1.267
Consensus CDS ProjectCCDS38818.1
International Mouse Knockout Project StatusAlg6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007982 VEGA Gene Model | MGI Sequence Detail 47797 C57BL/6J ±  kb
transcript OTTMUST00000018089 VEGA | MGI Sequence Detail 3079 Not Applicable 
polypeptide OTTMUSP00000008309 VEGA | MGI Sequence Detail 507 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(22) UniProt(3)
Polymorphisms SNPs within 2kb(225 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004856 Glycosyl transferase, ALG6/ALG8
Protein Ontology PR:000003946 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173488 Pandey P, et al., Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease. BMC Syst Biol. 2011;5:56
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory