Ankrd52 MGI Mouse Gene Detail - MGI:2444029

Symbol

Ankrd52
Name

ankyrin repeat domain 52
Synonyms

G431002C21Rik

Feature Type

protein coding gene
IDs

MGI:2444029
NCBI Gene: 237615
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr10:128212993-128229875 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 76.54 cM
Mapping Data

1 experiment

SNPs within 2kb

117 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444029	protein coding gene	Chr10:128212984-128244573 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017862	protein coding gene	Chr10:132109778-132142381 (+)
A/J	MGP_AJ_G0017837	protein coding gene	Chr10:126803009-126835794 (+)
AKR/J	MGP_AKRJ_G0017800	protein coding gene	Chr10:130527145-130558508 (+)
BALB/cJ	MGP_BALBcJ_G0017801	protein coding gene	Chr10:127186439-127218049 (+)
C3H/HeJ	MGP_C3HHeJ_G0017624	protein coding gene	Chr10:130690486-130721979 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018256	protein coding gene	Chr10:136587108-136619816 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015934	protein coding gene	Chr10:120738359-120768886 (+)
CAST/EiJ	MGP_CASTEiJ_G0017185	protein coding gene	Chr10:131400534-131432414 (+)
CBA/J	MGP_CBAJ_G0017594	protein coding gene	Chr10:142135129-142166498 (+)
DBA/2J	MGP_DBA2J_G0017700	protein coding gene	Chr10:125865141-125899642 (+)
FVB/NJ	MGP_FVBNJ_G0017695	protein coding gene	Chr10:124794388-124826553 (+)
LP/J	MGP_LPJ_G0017774	protein coding gene	Chr10:132703545-132735756 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017723	protein coding gene	Chr10:144740642-144772088 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018296	protein coding gene	Chr10:130627179-130658872 (+)
PWK/PhJ	MGP_PWKPhJ_G0016970	protein coding gene	Chr10:126124894-126156781 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016759	protein coding gene	Chr10:129719938-129752387 (+)
WSB/EiJ	MGP_WSBEiJ_G0017244	protein coding gene	Chr10:130841391-130874349 (+)

Human Ortholog

ANKRD52, ankyrin repeat domain 52

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ANKRD52, ankyrin repeat domain 52
Synonyms

ANKRD33
Links

HGNC:26614

NCBI Gene ID: 283373

neXtProt AC: NX_Q8NB46

UniProt: Q8NB46
Chr Location

12q13.3; chr12:56237807-56258384 (-) GRCh38

MGI Vertebrate Homology

Ankrd52 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: ANKRD52
Gene Tree

Ankrd52

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Endonuclease-mediated

1
Gene trapped

7
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

37 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

3
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

31

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ankrd52

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All Sequences

37
RefSeq

2
UniProt

4
CCDS

CCDS24274.1

Ensembl

ENSMUSG00000014498 (Evidence)
NCBI Gene

237615

			Length	Strain/Species	Flank
genomic	237615	NCBI Gene Model \| MGI Sequence Detail	16883	C57BL/6J	± kb
transcript	NM_172790	RefSeq \| MGI Sequence Detail	6615	C57BL/6
polypeptide	Q8BTI7	UniProt \| EBI \| MGI Sequence Detail	1076	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000004049 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

(term hierarchy)
InterPro Domains

IPR002110 Ankyrin repeat

IPR036770 Ankyrin repeat-containing domain superfamily

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All nucleic 31

cDNA 31

Microarray probesets 1

Summaries

All 26

Gene Ontology 1

Phenotypes 8
Earliest

J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Ankrd52:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr96408	Chr10:128212336-128212382 (+)	-634 bp
Tssr96409	Chr10:128212955-128213024 (+)	-3 bp
Tssr96410	Chr10:128227133-128227135 (+)	14,141 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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