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Dpp9 Gene Detail
Summary
  • Symbol
    Dpp9
  • Name
    dipeptidylpeptidase 9
  • Synonyms
    6430584G11Rik, DPRP2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443967
    NCBI Gene: 224897
  • Gene Overview
    MyGene.info: DPP9
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:56186807-56218889 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 29.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    6 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443967
protein coding gene Chr17:56186674-56218889 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023918
protein coding gene Chr17:57840968-57873161 (-)
A/J MGP_AJ_G0023877
protein coding gene Chr17:56276543-56310217 (-)
AKR/J MGP_AKRJ_G0023847
protein coding gene Chr17:56950036-56985863 (-)
BALB/cJ MGP_BALBcJ_G0023879
protein coding gene Chr17:56100654-56132421 (-)
C3H/HeJ MGP_C3HHeJ_G0023642
protein coding gene Chr17:57661579-57694752 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024323
protein coding gene Chr17:60120487-60155569 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021770
protein coding gene Chr17:52773545-52806771 (-)
CAST/EiJ MGP_CASTEiJ_G0023125
protein coding gene Chr17:57975178-58007293 (-)
CBA/J MGP_CBAJ_G0023619
protein coding gene Chr17:62419489-62456308 (-)
DBA/2J MGP_DBA2J_G0023747
protein coding gene Chr17:54992447-55024765 (-)
FVB/NJ MGP_FVBNJ_G0023713
protein coding gene Chr17:54515676-54549222 (-)
LP/J MGP_LPJ_G0023827
protein coding gene Chr17:58540502-58574504 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023740
protein coding gene Chr17:61968808-62003723 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024368
protein coding gene Chr17:57328328-57361986 (-)
PWK/PhJ MGP_PWKPhJ_G0022870
protein coding gene Chr17:54340637-54373879 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022682
protein coding gene Chr17:54097687-54129660 (-)
WSB/EiJ MGP_WSBEiJ_G0023189
protein coding gene Chr17:57939167-57971270 (-)



Homology
more
  • Human Ortholog
    DPP9, dipeptidyl peptidase 9
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DPP9, dipeptidyl peptidase 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DP9, DPLP9, DPP IX, DPRP2, DPRP-2
  • Links
    NCBI Gene ID: 91039
    neXtProt AC: NX_Q86TI2
    UniProt: Q86TI2

  • Chr Location
    19p13.3; chr19:4675226-4723843 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotypes from 4 alleles in 3 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutants display partial neonatal lethality and complete lethality at preweaning stages with defects suckling due to undeveveloped tongue muscle.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000001229 Ensembl Gene Model | MGI Sequence Detail 32083 C57BL/6J ±  kb
    transcript ENSMUST00000038794 Ensembl | MGI Sequence Detail 3374 Not Applicable  
    polypeptide ENSMUSP00000046604 Ensembl | MGI Sequence Detail 862 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 73
      cDNA 72
      Other 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 16
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:251322 Kim M, et al., DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect. Dev Biol. 2017 Nov 15;431(2):297-308

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory