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Dpp9 Gene Detail
Summary
  • Symbol
    Dpp9
  • Name
    dipeptidylpeptidase 9
  • Synonyms
    6430584G11Rik, DPRP2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443967
    NCBI Gene: 224897
  • Gene Overview
    MyGene.info: DPP9
Location & Maps
more
  • Sequence Map
    Chr17:56186682-56218889 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32208 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 29.20 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DPP9, dipeptidyl peptidase 9
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DPP9, dipeptidyl peptidase 9
    Orthology source: HomoloGene
  • Synonyms
    DP9, DPLP9, DPRP2, DPRP-2
  • Links
    NCBI Gene ID: 91039
    neXtProt AC: NX_Q86TI2

  • Chr Location
    19p13.3; chr19:4675226-4723843 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutants display partial neonatal lethality and complete lethality at preweaning stages.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001229 Ensembl Gene Model | MGI Sequence Detail 32208 C57BL/6J ±  kb
transcript ENSMUST00000038794 Ensembl | MGI Sequence Detail 3509 Not Applicable  
polypeptide ENSMUSP00000046604 Ensembl | MGI Sequence Detail 862 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    6 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000006664 dipeptidyl peptidase 9
  • EC
  • InterPro Domains
    IPR029058 Alpha/Beta hydrolase fold
    IPR002469 Dipeptidylpeptidase IV, N-terminal domain
    IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
Molecular
Reagents
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  • All nucleic 71
    cDNA 71

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory