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Dpp9
Gene Detail
Symbol

Name
ID
Dpp9
dipeptidylpeptidase 9
MGI:2443967
Synonyms
6430584G11Rik, DPRP2
Feature Type
protein coding gene
Genetic Map
Chromosome 17
29.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:56186682-56218889 bp, - strand
From Ensembl annotation of GRCm38

  32208 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16385  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Dpp9

Human
homologs
Human Homolog DPP9, dipeptidyl-peptidase 9
NCBI Gene ID 91039
neXtProt AC  NX_Q86TI2
Human Synonyms  DP9, DPLP9, DPRP2, DPRP-2
Human Chr (Location)  19p13.3; chr19:4675226-4723843 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(12) Targeted(9)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutants display partial neonatal lethality and complete lethality at preweaning stages.
 
Interactions
Dpp9 interacts with 159 markers (Mir1a-1, Mir1b, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process proteolysis
Component cytoplasm, membrane
Function aminopeptidase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(71)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(71) cDNA(71)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000001229 (Evidence)
Entrez Gene224897 (Evidence)
UniGene205535
DFCITC1601969, TC1626634, TC1577316
DoTSDT.101303782, DT.91418578, DT.488725
NIA Mouse Gene IndexU037942
EC3.4.14.5
Consensus CDS ProjectCCDS37663.1
International Mouse Knockout Project StatusDpp9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001229 Ensembl Gene Model | MGI Sequence Detail 32208 C57BL/6J ±  kb
transcript ENSMUST00000038794 Ensembl | MGI Sequence Detail 3509 Not Applicable 
polypeptide ENSMUSP00000046604 Ensembl | MGI Sequence Detail 862 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(7) UniProt(1)
Polymorphisms
SNPs within 2kb(6 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002469 Peptidase S9B, dipeptidylpeptidase IV N-terminal
InterPro IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
Protein Ontology PR:000006664 dipeptidyl peptidase 9
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:209219 Gall MG, et al., Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality. PLoS One. 2013;8(11):e78378
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory