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Zfp516 Gene Detail
Summary
  • Symbol
    Zfp516
  • Name
    zinc finger protein 516
  • Synonyms
    C330029B10Rik, mKIAA0222, Zfp26l
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443957
    NCBI Gene: 329003
  • Gene Overview
    MyGene.info: ZNF516
Location & Maps
more
  • Sequence Map
    Chr18:82910879-83005314 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      94436 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 57.39 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ZNF516, zinc finger protein 516
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZNF516, zinc finger protein 516
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HsT287
  • Links
    NCBI Gene ID: 9658
    neXtProt AC: NX_Q92618

  • Chr Location
    18q23; chr18:76357682-76495234 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    92
  • Gene trapped
    91
  • Transposon induced
    1
  • Genomic Mutations
    1 involving Zfp516
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058881 Ensembl Gene Model | MGI Sequence Detail 94436 C57BL/6J ±  kb
transcript ENSMUST00000171238 Ensembl | MGI Sequence Detail 7725 Not Applicable  
polypeptide ENSMUSP00000126629 Ensembl | MGI Sequence Detail 1157 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    507 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000017948 zinc finger protein 516
  • InterPro Domains
    IPR007087 Zinc finger, C2H2
    IPR015880 Zinc finger, C2H2-like
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
less
  • All nucleic 58
    cDNA 56
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:1926951
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:218161 Dempersmier J, et al., Cold-Inducible Zfp516 Activates UCP1 Transcription to Promote Browning of White Fat and Development of Brown Fat. Mol Cell. 2015 Jan 22;57(2):235-46

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory