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Mmp25 Gene Detail
Summary
  • Symbol
    Mmp25
  • Name
    matrix metallopeptidase 25
  • Synonyms
    F730048C11Rik, Leukolysin, MT6-MMP
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443938
    NCBI Gene: 240047
  • Gene Overview
    MyGene.info: MMP25
Location & Maps
more
  • Sequence Map
    Chr17:23629458-23645269 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15812 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 11.87 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MMP25, matrix metallopeptidase 25
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MMP25, matrix metallopeptidase 25
    Orthology source: HomoloGene
  • Synonyms
    MMP20, MMP20A, MMP-25, MMPL1, MT6MMP, MT6-MMP, MTMMP6, MT-MMP6, MT-MMP 6
  • Links
    NCBI Gene ID: 64386
    neXtProt AC: NX_Q9NPA2

  • Chr Location
    16p13.3; chr16:3045963-3060729 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 240047 NCBI Gene Model | MGI Sequence Detail 15812 C57BL/6J ±  kb
transcript NM_001033339 RefSeq | MGI Sequence Detail 3670 C57BL/6  
polypeptide Q3U435 UniProt | EBI | MGI Sequence Detail 615 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    145 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 1
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:224428 Newby AC, Metalloproteinases promote plaque rupture and myocardial infarction: A persuasive concept waiting for clinical translation. Matrix Biol. 2015 May-Jul;44-46:157-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory