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Lcor
Gene Detail
 Symbol
Name
ID
Lcor
ligand dependent nuclear receptor corepressor
MGI:2443930
Synonyms 3110023F06Rik, A630025C20Rik, mKIAA1795, Mlr2
Feature Type protein coding gene
Genetic Map
Chromosome 19
34.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:41549639-41559781 bp, + strand
From NCBI annotation of GRCm38

  10143 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18153  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 chicken; 1 zebrafish

Gene Tree: Lcor

Human
homologs
Human Homolog LCOR, ligand dependent nuclear receptor corepressor
NCBI Gene ID 84458
neXtProt AC  NX_Q96JN0
Human Synonyms  MLR2
Human Chr (Location)  10q24; chr10:96832260-96964441 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from APF )
Interactions
Lcor interacts with 412 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-templated, ...
Component nucleus
Function DNA binding, sequence-specific DNA binding transcription factor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (240)    Tissues (130)    Images (38)
Theiler Stages: 2, 3, 4, 5, 17, 19, 20, 21, 22, 23, 24, 25, 27, 28
Assay TypeResults
RNA in situ 232
RT-PCR 8
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(17) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000025019 (Evidence)
Entrez Gene212391 (Evidence)
DFCITC1584325, TC1602839, TC1628519, TC1718682
DoTSDT.101361151, DT.101724315, DT.524571, DT.55160968, DT.55190112, DT.99855695
NIA Mouse Gene IndexU043727, U059342, U088219
Consensus CDS ProjectCCDS29810.1
International Mouse Knockout Project StatusLcor
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 212391 NCBI Gene Model | MGI Sequence Detail 10143 C57BL/6J ±  kb
transcript NM_172154 RefSeq | MGI Sequence Detail 4663 C57BL/6 
polypeptide Q6ZPI3 UniProt | EBI | MGI Sequence Detail 433 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007889 DNA binding HTH domain, Psq-type
InterPro IPR009057 Homeodomain-like
Protein Ontology PR:000009730 ligand-dependent corepressor
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:1920403

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory