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Thsd7b Gene Detail
Summary
  • Symbol
    Thsd7b
  • Name
    thrombospondin, type I, domain containing 7B
  • Synonyms
    1700074E13Rik, D130067I03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443925
    NCBI Gene: 210417
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:129273304-130219278 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 56.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5393 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443925
protein coding gene Chr1:129273302-130219278 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016432
protein coding gene Chr1:132580174-133540512 (+)
A/J MGP_AJ_G0016415
protein coding gene Chr1:127622367-128561597 (+)
AKR/J MGP_AKRJ_G0016380
protein coding gene Chr1:131411988-132388278 (+)
BALB/cJ MGP_BALBcJ_G0016375
protein coding gene Chr1:127996094-128941339 (+)
C3H/HeJ MGP_C3HHeJ_G0016201
protein coding gene Chr1:131564318-132525317 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016836
protein coding gene Chr1:137542691-138526720 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014550
protein coding gene Chr1:120915614-121796062 (+)
CAST/EiJ MGP_CASTEiJ_G0015782
protein coding gene Chr1:130573006-131556401 (+)
CBA/J MGP_CBAJ_G0016174
protein coding gene Chr1:142207458-143278920 (+)
DBA/2J MGP_DBA2J_G0016280
protein coding gene Chr1:126658025-127572622 (+)
FVB/NJ MGP_FVBNJ_G0016279
protein coding gene Chr1:125350659-126272850 (+)
LP/J MGP_LPJ_G0016351
protein coding gene Chr1:133927630-134902986 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016304
protein coding gene Chr1:148002367-149092547 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016872
protein coding gene Chr1:131187430-132159833 (+)
PWK/PhJ MGP_PWKPhJ_G0015568
protein coding gene Chr1:125634190-126561951 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015356
protein coding gene Chr1:130134058-131099664 (+)
WSB/EiJ MGP_WSBEiJ_G0015844
protein coding gene Chr1:131136731-132124568 (+)



Homology
more
  • Human Ortholog
    THSD7B, thrombospondin type 1 domain containing 7B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    THSD7B, thrombospondin type 1 domain containing 7B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 80731
    UniProt: Q9C0I4

  • Chr Location
    2q22.1; chr2:136765562-137677712 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 210417 NCBI Gene Model | MGI Sequence Detail 945975 C57BL/6J ±  kb
transcript NM_172485 RefSeq | MGI Sequence Detail 6283 C57BL/6  
polypeptide Q6P4U0 UniProt | EBI | MGI Sequence Detail 1607 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032684 thrombospondin type-1 domain-containing protein 7B
  • InterPro Domains
    IPR000884 Thrombospondin type-1 (TSP1) repeat
    IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Molecular
Reagents
less
  • All nucleic 23
    cDNA 22
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925716
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory