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Lipi
Gene Detail
 Symbol
Name
ID
Lipi
lipase, member I
MGI:2443868
Synonyms D930038D03Rik, lpd1
Feature Type protein coding gene
Genetic Map
Chromosome 16
43.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:75540514-75586056 bp, - strand
From Ensembl annotation of GRCm38

  45543 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77864  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Lipi

Human
homologs
Human Homolog LIPI, lipase, member I
NCBI Gene ID 149998
neXtProt AC  NX_Q6XZB0
Human Synonyms  CT17, LPDL, PLA1C
Human Chr (Location)  21q11.2; chr21:14108463-14211040 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human LIPI
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(2) Transgenic(1)
Genomic Mutations involving Lipi (1)
Incidental mutations (data from APF )
 
Mice homozygous for a transgenic gene disruption exhibit postnatal lethality, tremors, abnormal gait, decreased body weight, retarded hair growth, and a defect in triglyceride metabolism resulting in hypertriglyceridemia and hepatic steatosis.
 
Interactions
Lipi interacts with 131 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process lipid catabolic process
Component extracellular space, plasma membrane
Function heparin binding, phospholipase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (18)    Tissues (2)    Images (11)
Theiler Stages: 23
Assay TypeResults
RNA in situ 18
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000032948 (Evidence)
Entrez Gene320355 (Evidence)
UniGene99517
DFCITC1591250, TC1619804
DoTSDT.101275517, DT.55135557
NIA Mouse Gene IndexU037210
Consensus CDS ProjectCCDS28272.1
International Mouse Knockout Project StatusLipi
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032948 Ensembl Gene Model | MGI Sequence Detail 45543 C57BL/6J ±  kb
transcript ENSMUST00000062721 Ensembl | MGI Sequence Detail 2077 Not Applicable 
polypeptide ENSMUSP00000053447 Ensembl | MGI Sequence Detail 111 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(7) UniProt(1)
Polymorphisms SNPs within 2kb(151 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000734 Lipase
References (Earliest) J:46789 Wen XY, et al., Characterization of lpd (lipid defect): a novel mutation on mouse chromosome 16 associated with a defect in triglyceride metabolism. Hum Mol Genet. 1998 Apr;7(4):743-50
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory