About   Help   FAQ
Pcif1 Gene Detail
Summary
  • Symbol
    Pcif1
  • Name
    phosphorylated CTD interacting factor 1
  • Synonyms
    2310022K11Rik, F730014I05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443858
    NCBI Gene: 228866
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164879368-164891440 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443858
protein coding gene Chr2:164879304-164894454 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026881
protein coding gene Chr2:170391037-170407478 (+)
A/J MGP_AJ_G0026848
protein coding gene Chr2:163417792-163432959 (+)
AKR/J MGP_AKRJ_G0026819
protein coding gene Chr2:168297537-168312641 (+)
BALB/cJ MGP_BALBcJ_G0026857
protein coding gene Chr2:163785121-163800010 (+)
C3H/HeJ MGP_C3HHeJ_G0026599
protein coding gene Chr2:168644123-168660146 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027304
protein coding gene Chr2:175330740-175346828 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024675
protein coding gene Chr2:156825566-156840431 (+)
CAST/EiJ MGP_CASTEiJ_G0026057
protein coding gene Chr2:169057257-169074061 (+)
CBA/J MGP_CBAJ_G0026576
protein coding gene Chr2:181694200-181711568 (+)
DBA/2J MGP_DBA2J_G0026714
protein coding gene Chr2:162583569-162599745 (+)
FVB/NJ MGP_FVBNJ_G0026680
protein coding gene Chr2:161006193-161021583 (+)
LP/J MGP_LPJ_G0026816
protein coding gene Chr2:170447147-170462148 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026699
protein coding gene Chr2:185238153-185253100 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027361
protein coding gene Chr2:168181928-168196796 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025595
protein coding gene Chr2:167086163-167102273 (+)
WSB/EiJ MGP_WSBEiJ_G0026130
protein coding gene Chr2:169062918-169079302 (+)



Homology
more
  • Human Ortholog
    PCIF1, phosphorylated CTD interacting factor 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PCIF1, phosphorylated CTD interacting factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf67, CAPAM, hCAPAM, hPCIF1, PPP1R121
  • Links
    NCBI Gene ID: 63935
    neXtProt AC: NX_Q9H4Z3
    UniProt: Q9H4Z3

  • Chr Location
    20q13.12; chr20:45934674-45948023 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced body weight.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 228866 NCBI Gene Model | MGI Sequence Detail 12073 C57BL/6J ±  kb
    transcript NM_001374126 RefSeq | MGI Sequence Detail 3887 C57BL/6  
    polypeptide P59114 UniProt | EBI | MGI Sequence Detail 706 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 111
      cDNA 111

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1917532
    References
    more
    • Summaries
      All 37
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:293136 Pandey RR, et al., The Mammalian Cap-Specific m(6)Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues. Cell Rep. 2020 Aug 18;32(7):108038

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/10/2020
    MGI 6.16
    The Jackson Laboratory