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Arhgap29 Gene Detail
Summary
  • Symbol
    Arhgap29
  • Name
    Rho GTPase activating protein 29
  • Synonyms
    6720461J18Rik, B130017I01Rik, C76601, Parg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443818
    NCBI Gene: 214137
Location & Maps
more
  • Sequence Map
    Chr3:121952541-122016753 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      64213 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 52.94 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ARHGAP29, Rho GTPase activating protein 29
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ARHGAP29, Rho GTPase activating protein 29
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PARG1
  • Links
    NCBI Gene ID: 9411
    neXtProt AC: NX_Q52LW3

  • Chr Location
    1p22.1; chr1:94168907-94275068 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Arhgap29
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    81
  • Tissues
    6
  • cDNA Data
    151
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026603 VEGA Gene Model | MGI Sequence Detail 64213 C57BL/6J ±  kb
transcript OTTMUST00000065825 VEGA | MGI Sequence Detail 5787 Not Applicable  
polypeptide OTTMUSP00000032859 VEGA | MGI Sequence Detail 1266 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    530 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000004235 rho GTPase-activating protein 29
  • InterPro Domains
    IPR031160 F-BAR domain
    IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
    IPR000198 Rho GTPase-activating protein domain
    IPR008936 Rho GTPase activation protein
Molecular
Reagents
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  • All nucleic 152
    cDNA 152

    Microarray probesets 2
Other
Accession IDs
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MGI:1924435, MGI:2139903, MGI:2140040
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:202648 Leslie EJ, et al., Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22. Birth Defects Res A Clin Mol Teratol. 2012 Nov;94(11):934-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/27/2016
MGI 6.05 		The Jackson Laboratory