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Kctd8 Gene Detail
Summary
  • Symbol
    Kctd8
  • Name
    potassium channel tetramerisation domain containing 8
  • Synonyms
    A730087N02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443804
    NCBI Gene: 243043
Location & Maps
more
  • Sequence Map
    Chr5:69109285-69341679 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      232395 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 37.01 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    KCTD8, potassium channel tetramerization domain containing 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCTD8, potassium channel tetramerization domain containing 8
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 386617
    neXtProt AC: NX_Q6ZWB6

  • Chr Location
    4p13; chr4:44173903-44448885 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 18464
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: KCTD8
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Kctd8
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028715 VEGA Gene Model | MGI Sequence Detail 232395 C57BL/6J ±  kb
transcript OTTMUST00000071114 VEGA | MGI Sequence Detail 2859 Not Applicable  
polypeptide OTTMUSP00000036370 VEGA | MGI Sequence Detail 476 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    615 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031995 BTB/POZ domain-containing protein KCTD8
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR011333 SKP1/BTB/POZ domain
Molecular
Reagents
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  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 22
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 18
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory