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Kctd8 Gene Detail
Summary
  • Symbol
    Kctd8
  • Name
    potassium channel tetramerisation domain containing 8
  • Synonyms
    A730087N02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443804
    NCBI Gene: 243043
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:69109285-69341679 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 37.01 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    615 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443804
protein coding gene Chr5:69109285-69341709 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029601
protein coding gene Chr5:68948801-69189200 (-)
A/J MGP_AJ_G0029569
protein coding gene Chr5:66352929-66582974 (-)
AKR/J MGP_AKRJ_G0029517
protein coding gene Chr5:68470032-68704233 (-)
BALB/cJ MGP_BALBcJ_G0029578
protein coding gene Chr5:67029270-67264028 (-)
C3H/HeJ MGP_C3HHeJ_G0029301
protein coding gene Chr5:68824697-69065217 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030032
protein coding gene Chr5:71813871-72057599 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027272
protein coding gene Chr5:62316496-62547648 (-)
CAST/EiJ MGP_CASTEiJ_G0028709
protein coding gene Chr5:67961819-68219664 (-)
CBA/J MGP_CBAJ_G0029270
protein coding gene Chr5:74129276-74390203 (-)
DBA/2J MGP_DBA2J_G0029416
protein coding gene Chr5:66380198-66611128 (-)
FVB/NJ MGP_FVBNJ_G0029376
protein coding gene Chr5:65625076-65866703 (-)
LP/J MGP_LPJ_G0029501
protein coding gene Chr5:69415596-69652695 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029404
protein coding gene Chr5:77044277-77329448 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030065
protein coding gene Chr5:68127051-68362376 (-)
PWK/PhJ MGP_PWKPhJ_G0028433
protein coding gene Chr5:65405031-65645020 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028267
protein coding gene Chr5:67493143-67735018 (-)
WSB/EiJ MGP_WSBEiJ_G0028789
protein coding gene Chr5:68355985-68607272 (-)



Homology
more
  • Human Ortholog
    KCTD8, potassium channel tetramerization domain containing 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCTD8, potassium channel tetramerization domain containing 8
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 386617
    neXtProt AC: NX_Q6ZWB6
    UniProt: Q6ZWB6

  • Chr Location
    4p13; chr4:44173903-44448885 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18464
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KCTD8
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037653 Ensembl Gene Model | MGI Sequence Detail 232395 C57BL/6J ±  kb
transcript ENSMUST00000054095 Ensembl | MGI Sequence Detail 2859 Not Applicable  
polypeptide ENSMUSP00000055326 Ensembl | MGI Sequence Detail 476 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 18
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory