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Etnk2
Gene Detail
Symbol

Name
ID
Etnk2
ethanolamine kinase 2
MGI:2443760
Synonyms
4933417N20Rik, Eki2
Feature Type
protein coding gene
Genetic Map
Chromosome 1
57.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:133363572-133380336 bp, + strand
From VEGA annotation of GRCm38

  16765 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10072  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: ETNK2
Gene Tree: Etnk2

Human
homologs
ETNK2, ethanolamine kinase 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 55224
neXtProt AC: NX_Q9NVF9

Human Synonyms: EKI2, HMFT1716

Human Chr (Location): 1q32.1; chr1:204131061-204152182 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous mutation of this gene results in maternal-specific intrauterine growth retardation resulting in reduced litter size and perinatal lethality due to extensive placental thrombosis.
 
Interactions
Etnk2 interacts with 137 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process in utero embryonic development, lipid metabolic process, ...
Component cellular_component
Function ATP binding, ethanolamine kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (183)    Tissues (163)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 178
RT-PCR 5
cDNA source data(25)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN etnk2    NEW 
Molecular
reagents
All nucleic(26) cDNA(25) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026805 (Evidence)
Ensembl Gene Model ENSMUSG00000070644 (Evidence)
Entrez Gene 214253 (Evidence)
UniGene 52111
DFCI TC1610943, TC1618383, TC1609885, TC1585929
DoTS DT.101185153, DT.40187735, DT.102555335, DT.97399144
NIA Mouse Gene Index U000817
EC 2.7.1.82
Consensus CDS Project CCDS15296.2
International Mouse Phenotyping Consortium Status Etnk2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026805 VEGA Gene Model | MGI Sequence Detail 16765 C57BL/6J ±  kb
transcript OTTMUST00000066290 VEGA | MGI Sequence Detail 2297 Not Applicable 
polypeptide OTTMUSP00000033202 VEGA | MGI Sequence Detail 385 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(362 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011009 Protein kinase-like domain
Protein Ontology PR:000007220 ethanolamine kinase 2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)
Other
accession IDs
MGI:2138175

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory