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Etnk2 Gene Detail
Summary
  • Symbol
    Etnk2
  • Name
    ethanolamine kinase 2
  • Synonyms
    4933417N20Rik, Eki2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443760
    NCBI Gene: 214253
Location & Maps
more
  • Sequence Map
    Chr1:133363572-133380336 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16765 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 57.91 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ETNK2, ethanolamine kinase 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ETNK2, ethanolamine kinase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EKI2, HMFT1716
  • Links
    NCBI Gene ID: 55224
    neXtProt AC: NX_Q9NVF9

  • Chr Location
    1q32.1; chr1:204131061-204152182 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Etnk2
  • Incidental Mutations
Homozygous mutation of this gene results in maternal-specific intrauterine growth retardation resulting in reduced litter size and perinatal lethality due to extensive placental thrombosis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026805 VEGA Gene Model | MGI Sequence Detail 16765 C57BL/6J ±  kb
transcript OTTMUST00000066290 VEGA | MGI Sequence Detail 2297 Not Applicable  
polypeptide OTTMUSP00000033202 VEGA | MGI Sequence Detail 385 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    352 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 25
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138175
References
more
  • Summaries
    All 24
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory