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Fbxo40 Gene Detail
Summary
  • Symbol
    Fbxo40
  • Name
    F-box protein 40
  • Synonyms
    9830003A13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443753
    NCBI Gene: 207215
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:36783822-36810829 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 26.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    601 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443753
 protein coding gene Chr16:36783822-36811321 (-)
129S1/SvImJ ENSMUSG00200027422
 protein coding gene Chr16:33719621-33746627 (-)
A/J ENSMUSG00195010165
 protein coding gene Chr16:33266056-33293067 (-)
AKR/J ENSMUSG00220025561
 protein coding gene Chr16:33643694-33670696 (-)
BALB/cJ ENSMUSG00180012853
 protein coding gene Chr16:33481668-33508680 (-)
C3H/HeJ ENSMUSG00175029427
 protein coding gene Chr16:33702035-33729045 (-)
C57BL/6NJ ENSMUSG00215015268
 protein coding gene Chr16:33555213-33582219 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020724
 protein coding gene Chr16:34008457-34029525 (-)
CAST/EiJ ENSTCUG00005028161
 protein coding gene Chr16:33974245-34001282 (-)
CBA/J ENSMUSG00210026717
 protein coding gene Chr16:33759115-33786126 (-)
DBA/2J ENSMUSG00185022991
 protein coding gene Chr16:33662150-33689160 (-)
FVB/NJ ENSMUSG00205013960
 protein coding gene Chr16:33619082-33646089 (-)
JF1/MsJ ENSUMUG00000018263
 protein coding gene Chr16:33882920-33903935 (-)
LP/J ENSMUSG00230025878
 protein coding gene Chr16:36234340-36261351 (-)
NOD/ShiLtJ ENSMUSG00190022389
 protein coding gene Chr16:33780507-33807511 (-)
NZO/HlLtJ ENSMUSG00225038273
 protein coding gene Chr16:39333701-39360711 (-)
PWK/PhJ ENSLUMG00010029300
 protein coding gene Chr16:33790754-33811732 (-)
SPRET/EiJ ENSMSPG00010016352
 protein coding gene Chr16:33762819-33784010 (-)
WSB/EiJ ENSIUOG00005024566
 protein coding gene Chr16:33831781-33858816 (-)



Homology
more
  • Human Ortholog
    FBXO40, F-box protein 40
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO40, F-box protein 40
  • Synonyms
    FBX40
  • Links
    NCBI Gene ID: 51725
    UniProt: Q9UH90

  • Chr Location
    3q13.33; chr3:121592886-121630434 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    607
  • Tissues
    2
  • cDNA Data
    9
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047746 Ensembl Gene Model | MGI Sequence Detail 27008 C57BL/6J ±  kb
transcript ENSMUST00000075869 Ensembl | MGI Sequence Detail 5137 Not Applicable  
polypeptide ENSMUSP00000075266 Ensembl | MGI Sequence Detail 710 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:296811 Zhang L, et al., Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40. Am J Physiol Endocrinol Metab. 2020 May 1;318(5):E625-E635
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory