About   Help   FAQ
Tnrc6b Gene Detail
Summary
  • Symbol
    Tnrc6b
  • Name
    trinucleotide repeat containing 6b
  • Synonyms
    2700090M07Rik, A730065C02Rik, D230019K20Rik, mKIAA1093
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443730
    NCBI Gene: 213988
  • Gene Overview
    MyGene.info: TNRC6B
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:80711313-80941085 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      229773 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.91 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TNRC6B, trinucleotide repeat containing 6B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TNRC6B, trinucleotide repeat containing 6B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23112
    neXtProt AC: NX_Q9UPQ9
    UniProt: Q9UPQ9

  • Chr Location
    22q13.1; chr22:40044817-40335808 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 66194
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TNRC6B
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit neonatal and postnatal lethality with decreased body weight and infertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047888 Ensembl Gene Model | MGI Sequence Detail 229773 C57BL/6J ±  kb
transcript ENSMUST00000067689 Ensembl | MGI Sequence Detail 17332 Not Applicable  
polypeptide ENSMUSP00000064336 Ensembl | MGI Sequence Detail 1810 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    729 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919875, MGI:2146082, MGI:2442182
References
more
  • Summaries
    All 58
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 33
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:248980 Guo H, et al., Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/12/2018
MGI 6.12
The Jackson Laboratory