About   Help   FAQ
Nlrp4a Gene Detail
Summary
  • Symbol
    Nlrp4a
  • Name
    NLR family, pyrin domain containing 4A
  • Synonyms
    E330028A19Rik, Nalp4a, Nalp9D, Nalp-eta
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443697
    NCBI Gene: 243880
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:26435113-26476142 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 14.78 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443697
protein coding gene Chr7:26435113-26476142 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031886
protein coding gene Chr7:24986772-25032778 (+)
A/J MGP_AJ_G0031866
protein coding gene Chr7:24349602-24402595 (+)
AKR/J MGP_AKRJ_G0031796
protein coding gene Chr7:24988611-25031393 (+)
BALB/cJ MGP_BALBcJ_G0031871
protein coding gene Chr7:24568221-24612254 (+)
C3H/HeJ MGP_C3HHeJ_G0031593
protein coding gene Chr7:25415404-25460076 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032333
protein coding gene Chr7:25794873-25851043 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029387
protein coding gene Chr7:25642459-25675475 (+)
CAST/EiJ MGP_CASTEiJ_G0030929
protein coding gene Chr7:18707496-18760747 (+)
CBA/J MGP_CBAJ_G0031558
protein coding gene Chr7:26844352-26890344 (+)
DBA/2J MGP_DBA2J_G0031709
protein coding gene Chr7:24232999-24282790 (+)
FVB/NJ MGP_FVBNJ_G0031666
protein coding gene Chr7:24318503-24359902 (+)
LP/J MGP_LPJ_G0031790
protein coding gene Chr7:25267149-25313317 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031699
protein coding gene Chr7:26471443-26522710 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032366
protein coding gene Chr7:24598968-24645299 (+)
PWK/PhJ MGP_PWKPhJ_G0030654
protein coding gene Chr7:19133337-19176288 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030483
protein coding gene Chr7:15654720-15710815 (+)
WSB/EiJ MGP_WSBEiJ_G0031033
protein coding gene Chr7:24863900-24909237 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 243880 NCBI Gene Model | MGI Sequence Detail 41030 C57BL/6J ±  kb
transcript NM_172896 RefSeq | MGI Sequence Detail 4259 C57BL/6  
polypeptide Q8BU40 UniProt | EBI | MGI Sequence Detail 982 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:216691 Li L, et al., Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouse. Carcinogenesis. 2014 Nov;35(11):2584-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory